University of Utah School of Medicine, Division of Microbiology & Immunology, Department of Pathology, Salt Lake City, UT 84121, USA.
University of Utah School of Medicine, Division of Microbiology & Immunology, Department of Pathology, Salt Lake City, UT 84121, USA.
Cell Host Microbe. 2019 Jan 9;25(1):3-5. doi: 10.1016/j.chom.2018.12.012.
Few studies have analyzed how diet-induced changes in the microbiota influence lupus. In this issue of Cell Host & Microbe, Zegarra-Ruiz et al. (2019) find that translocation of Lactobacillus reuteri from the gut to systemic organs worsens lupus. However, diets with resistant starch restrict L. reuteri growth and ameliorate disease.
很少有研究分析饮食引起的微生物组变化如何影响狼疮。在本期《细胞宿主与微生物》中,Zegarra-Ruiz 等人发现,从肠道到全身器官的罗伊氏乳杆菌易位会加重狼疮。然而,含有抗性淀粉的饮食会限制罗伊氏乳杆菌的生长并改善病情。