Campos Janaina K L, Araújo Tiago F da S, Brito Thaíse G da S, da Silva Ana P S, da Cunha Rebeca X, Martins Mônica B, da Silva Nicácio H, Dos Santos Bianka S, da Silva César A, Lima Vera L de M
Universidade Federal de Pernambuco (UFPE), Núcleo de Ciências da Vida, Centro Acadêmico do Agreste, Laboratório Morfofuncional, Rodovia BR 104, Km 62, S/N-Nova Caruaru, Caruaru, PE 55014-908, Brazil.
Universidade Federal de Pernambuco (UFPE), Departamento de Bioquímica, Av. Prof. Moraes Rego, 1235-Cidade Universitária, Recife, PE 50670-901, Brazil.
Adv Pharmacol Sci. 2018 Dec 2;2018:8168526. doi: 10.1155/2018/8168526. eCollection 2018.
Mill. (Fabaceae) is known as anil or anileira and also with other names, due to the production of a blue pigment, which is commonly used for yarn dyeing. It is distributed in some states of Brazil (Pernambuco, Paraíba, Mato Grosso, São Paulo, Bahia, Pará, and others) and is used in the popular medicine as a febrifuge, antispasmodic, diuretic, abortive, analgesic, purgative, or soothing agent against stomach and urinary problems, jaundice, and ulcers and also as an insecticide. In addition, can be used as animal feed. This review aimed at providing important data on the botanical, distribution, ethnopharmacology, phytochemical, pharmacological, and toxicity of based on the scientific literature. Information on was gathered via the Internet (from Elsevier, NCBI, and Sci-Hub) and libraries in the period from February to March 2016. More than 40 chemical compounds have been identified and a few compounds isolated, and the main origins are the essential oils, organic extracts, and aqueous extracts of different parts of the plant. and its active compounds possess wide pharmacological actions in the literature, such as anti-inflammatory, antibacterial, antifungal, antioxidative, antitumor, antimutagenic, anticonvulsant, gastroprotective, and hepatoprotective activities. Therefore, as an important traditional popular medicine, further studies on are required for the development of new drugs and therapeutics for various diseases.
Mill.（豆科）因能产生一种常用于纱线染色的蓝色色素而被称为anil或anileira，也有其他名称。它分布于巴西的一些州（伯南布哥州、帕拉伊巴州、马托格罗索州、圣保罗州、巴伊亚州、帕拉州等），在民间医学中用作退烧药、解痉剂、利尿剂、堕胎药、止痛剂、泻药，或用于缓解胃部和泌尿系统问题、黄疸和溃疡的舒缓剂，还用作杀虫剂。此外，它还可用作动物饲料。本综述旨在根据科学文献提供有关Mill.的植物学、分布、民族药理学、植物化学、药理学和毒性的重要数据。关于Mill.的信息是在2016年2月至3月期间通过互联网（来自爱思唯尔、美国国立医学图书馆和Sci-Hub）和图书馆收集的。已鉴定出40多种化合物并分离出了几种化合物，其主要来源是植物不同部位的精油、有机提取物和水提取物。在文献中，Mill.及其活性化合物具有广泛的药理作用，如抗炎、抗菌、抗真菌、抗氧化、抗肿瘤、抗诱变、抗惊厥、胃保护和肝保护活性。因此，作为一种重要的传统民间药物，需要对Mill.进行进一步研究，以开发针对各种疾病的新药和治疗方法。
