新型半合成多肽抗真菌抗生素LY121019的抗念珠菌活性及毒理学 - Suppr

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超能文献

Anti-Candida activity and toxicology of LY121019, a novel semisynthetic polypeptide antifungal antibiotic.

作者信息

Gordee R S, Zeckner D J, Howard L C, Alborn W E, Debono M

机构信息

Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana 46285.

出版信息

Ann N Y Acad Sci. 1988;544:294-309. doi: 10.1111/j.1749-6632.1988.tb40415.x.

DOI:10.1111/j.1749-6632.1988.tb40415.x

PMID:3063174

Abstract

摘要

相似文献

Anti-Candida activity and toxicology of LY121019, a novel semisynthetic polypeptide antifungal antibiotic.新型半合成多肽抗真菌抗生素LY121019的抗念珠菌活性及毒理学

Ann N Y Acad Sci. 1988;544:294-309. doi: 10.1111/j.1749-6632.1988.tb40415.x.

Evaluation of in vitro antifungal activity of LY121019.LY121019的体外抗真菌活性评估。

Eur J Clin Microbiol Infect Dis. 1988 Feb;7(1):77-80. doi: 10.1007/BF01962182.

A study of the antifungal activity of LY121019, a new echinocandin derivative.新型棘白菌素衍生物LY121019的抗真菌活性研究

Chemioterapia. 1988 Feb;7(1):33-7.

Comparative in vitro activity of LY121019 and amphotericin B against clinical isolates of Candida species.LY121019与两性霉素B对念珠菌属临床分离株的体外活性比较

Eur J Clin Microbiol Infect Dis. 1988 Feb;7(1):80-1. doi: 10.1007/BF01962183.

Susceptibility of nosocomial isolates of Candida species to LY121019 and other antifungal agents.医院分离的念珠菌属菌株对LY121019及其他抗真菌药物的敏感性。

Diagn Microbiol Infect Dis. 1989 Jan-Feb;12(1):1-4. doi: 10.1016/0732-8893(89)90035-7.

In vitro and in vivo anti-Candida activity and toxicology of LY121019.LY121019的体外和体内抗念珠菌活性及毒理学

J Antibiot (Tokyo). 1984 Sep;37(9):1054-65. doi: 10.7164/antibiotics.37.1054.

Fungicidal activity of cilofungin (LY121019) alone and in combination with anticapsin or other antifungal agents.

Eur J Clin Microbiol Infect Dis. 1989 Jun;8(6):564-7. doi: 10.1007/BF01967483.

Cilofungin (LY121019), an antifungal agent with specific activity against Candida albicans and Candida tropicalis.西洛芬净（LY121019），一种对白色念珠菌和热带念珠菌具有特异性活性的抗真菌剂。

Antimicrob Agents Chemother. 1988 Sep;32(9):1331-5. doi: 10.1128/AAC.32.9.1331.

Synthesis and evaluation of LY121019, a member of a series of semisynthetic analogues of the antifungal lipopeptide echinocandin B.

Ann N Y Acad Sci. 1988;544:152-67. doi: 10.1111/j.1749-6632.1988.tb40398.x.

In vitro activity of LY121019 against Candida species and Torulopsis glabrata.LY121019对念珠菌属和光滑球拟酵母菌的体外活性。

Eur J Clin Microbiol Infect Dis. 1988 Jun;7(3):432-3. doi: 10.1007/BF01962358.

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Antimicrob Agents Chemother. 1999 Sep;43(9):2148-55. doi: 10.1128/AAC.43.9.2148.

LY303366 exhibits rapid and potent fungicidal activity in flow cytometric assays of yeast viability.在酵母活力的流式细胞术检测中，LY303366表现出快速且强效的杀真菌活性。

Antimicrob Agents Chemother. 1999 Apr;43(4):830-5. doi: 10.1128/AAC.43.4.830.

Antifungal peptides: novel therapeutic compounds against emerging pathogens.抗真菌肽：对抗新出现病原体的新型治疗化合物。

Antimicrob Agents Chemother. 1999 Jan;43(1):1-11. doi: 10.1128/AAC.43.1.1.

Antifungal efficacy, safety, and single-dose pharmacokinetics of LY303366, a novel echinocandin B, in experimental pulmonary aspergillosis in persistently neutropenic rabbits.新型棘白菌素B（LY303366）在持续性中性粒细胞减少兔实验性肺曲霉病中的抗真菌疗效、安全性及单剂量药代动力学

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Comparative efficacies of cilofungin (Ly121019) and amphotericin B against disseminated Candida albicans infection in normal and granulocytopenic mice.西洛芬净（Ly121019）与两性霉素B对正常和粒细胞减少小鼠播散性白色念珠菌感染的疗效比较

Antimicrob Agents Chemother. 1993 Apr;37(4):729-36. doi: 10.1128/AAC.37.4.729.

Compounds active against cell walls of medically important fungi.对医学上重要真菌的细胞壁具有活性的化合物。

Clin Microbiol Rev. 1993 Jan;6(1):1-21. doi: 10.1128/CMR.6.1.1.

Use of cilofungin as direct fluorescent probe for monitoring antifungal drug-membrane interaction.使用西洛芬净作为直接荧光探针监测抗真菌药物与膜的相互作用。

Antimicrob Agents Chemother. 1994 Jun;38(6):1378-85. doi: 10.1128/AAC.38.6.1378.

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