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LY121019与两性霉素B对念珠菌属临床分离株的体外活性比较

Comparative in vitro activity of LY121019 and amphotericin B against clinical isolates of Candida species.

作者信息

Spitzer E D, Travis S J, Kobayashi G S

机构信息

Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri 63110.

出版信息

Eur J Clin Microbiol Infect Dis. 1988 Feb;7(1):80-1. doi: 10.1007/BF01962183.

Abstract

LY121019 and amphotericin B were equally active in vitro against most clinical isolates of Candida albicans and Candida tropicalis. Higher concentrations of LY121019 were required for inhibition of Candida glabrata. Other Candida species were inhibited by amphotericin B but not by LY121019.

摘要

LY121019和两性霉素B在体外对大多数白色念珠菌和热带念珠菌临床分离株的活性相当。抑制光滑念珠菌需要更高浓度的LY121019。其他念珠菌属被两性霉素B抑制,但不被LY121019抑制。

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