Kim Ji Eun, Kim Ji Young, Lee Hye Sun, Seok Suhyun, Kil Hae Keum
Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon.
Department of Anesthesiology and Pain Medicine, Severance Hospital, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul.
Medicine (Baltimore). 2019 Jan;98(2):e14087. doi: 10.1097/MD.0000000000014087.
The purpose of this study was to evaluate the effects of trigger point injection (TPI) and eutectic mixture local anesthetics (EMLA) cream on the postoperative shoulder pain in patients undergoing total laparoscopic hysterectomy.
In this randomized, single-blinded, and controlled study, total 75 patients were randomly allocated to TPI group (n = 25), EMLA group (n = 25), and control group (n = 25). TPI group received TPIs with 2 mL of 0.2% ropivacaine, and EMLA group received an occlusive dressing with EMLA cream 2 g on both shoulders. Overall, abdominal, and shoulder pains were evaluated at rest and in motion on postoperative day 3.
The incidence of shoulder pain was significantly reduced in EMLA group (56%) compared to control (88%) or TPI (88%) groups (P = .025 in both); the severity of shoulder pain was mitigated in EMLA and TPI groups compared to control group (P < .001, each). Consequently, the overall pain decreased in EMLA group and TPI group (P = .023). The patients with exercise habit (n = 31) showed lower incidence of pain than patients without exercise habit (n = 26) (P = .002, P = .005, and P = .037 in overall, abdominal, and shoulder pain, respectively). TPI or EMLA treatments decreased shoulder pain irrespective of exercise habit (P = .001 and P < .001, respectively), but decreased overall pain only in patients without exercise habit (P = .019). Lastly, EMLA lowered overall pain score at the time of first analgesic request in ward compared to control group (P = .02).
TPI and EMLA with occlusive dressing effectively reduced the shoulder pain after total laparoscopic hysterectomy.
本研究旨在评估触发点注射(TPI)和复方利多卡因(EMLA)乳膏对全腹腔镜子宫切除术后患者肩部疼痛的影响。
在这项随机、单盲对照研究中,75例患者被随机分为TPI组(n = 25)、EMLA组(n = 25)和对照组(n = 25)。TPI组接受2毫升0.2%罗哌卡因的触发点注射,EMLA组在双肩部使用2克EMLA乳膏并覆盖封闭敷料。术后第3天,评估静息和活动时的总体疼痛、腹部疼痛及肩部疼痛情况。
与对照组(88%)或TPI组(88%)相比,EMLA组肩部疼痛发生率显著降低(56%)(两者P值均为0.025);与对照组相比,EMLA组和TPI组肩部疼痛严重程度均减轻(每组P < 0.001)。因此,EMLA组和TPI组的总体疼痛减轻(P = 0.023)。有运动习惯的患者(n = 31)疼痛发生率低于无运动习惯的患者(n = 26)(总体疼痛、腹部疼痛及肩部疼痛的P值分别为0.002、0.005和0.037)。无论运动习惯如何,TPI或EMLA治疗均可减轻肩部疼痛(P值分别为0.001和P < 0.001),但仅在无运动习惯的患者中减轻总体疼痛(P = 0.019)。最后,与对照组相比,EMLA降低了病房中首次要求镇痛时的总体疼痛评分(P = 0.02)。
TPI和覆盖封闭敷料的EMLA可有效减轻全腹腔镜子宫切除术后的肩部疼痛。