牙科领域的噬菌体——现状与展望
Bacteriophages in Dentistry-State of the Art and Perspectives.
作者信息
Steier Liviu, de Oliveira Silvia Dias, de Figueiredo José Antonio Poli
机构信息
Visiting Professor, Post-Graduate Program in Dentistry, Federal University of Rio Grande do Sul-UFRGS, Porto Alegre 90035-003, Brazil.
Department of Biodiversity and Ecology, Pontifical Catholic University of Rio Grande do Sul-PUCRS, Porto Alegre 90619-900, Brazil.
出版信息
Dent J (Basel). 2019 Jan 9;7(1):6. doi: 10.3390/dj7010006.
Bacteriophages, viruses capable of killing bacteria, were discovered in 1915, but the interest in their study has been limited since the advent of antibiotics. Their use in dentistry is still very limited. The authors reviewed studies about bacteriophage structure, mode of action, uses in oral health, and possible future uses in dentistry associated with their possible action over biofilm, as well as the advantages and limitations of phage therapy.
噬菌体，即能够杀死细菌的病毒，于1915年被发现，但自抗生素问世以来，对其研究的兴趣一直有限。它们在牙科领域的应用仍然非常有限。作者回顾了关于噬菌体结构、作用方式、在口腔健康中的应用以及未来可能在牙科领域与它们对生物膜的潜在作用相关的应用，以及噬菌体疗法的优缺点的研究。
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