Department of Clinical Nursing, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.
Department of Nursing, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.
Int J Environ Res Public Health. 2019 Jan 9;16(2):175. doi: 10.3390/ijerph16020175.
The growing number of overweight and obese individuals is an alarming global problem; these conditions are risk factors for the development of health problems such as metabolic syndrome (MetS), type-2 diabetes, atherosclerosis, and cardiovascular disease. Numerous studies have suggested that vitamin D₃ deficiency plays a role in the pathogenesis of MetS. The aim of this study was to analyze the relationship between MetS and vitamin D₃ levels in women. Laboratory analysis demonstrated that only 26.89% of the participants had vitamin D₃ levels close to normal, and waist-to-hip ratio (WHR) measurements revealed android obesity in 75.63% of the women. The menstruating women more often suffered from vitamin D₃ deficiency, and less often had elevated vitamin D₃ levels. The conclusions are as follows: (1) There were no statistically significant relationships between vitamin D₃ levels and MetS parameters, namely the level of triglycerides, the levels of low- and high-density lipoproteins (LDL and HDL), the level of total cholesterol, and systolic and diastolic blood pressure (SBP and DBP). Vitamin D deficiency was only observed in the women with abdominal obesity. (2) Low vitamin D₃ levels were typical of perimenopausal women. Age was a variable correlating with vitamin D. (3) The presence of menstrual cycles was an important contributor to vitamin D levels. Vitamin D deficiency was significantly more common in the menstruating women.
超重和肥胖人群的数量不断增加，这是一个令人震惊的全球问题；这些情况是代谢综合征（MetS）、2 型糖尿病、动脉粥样硬化和心血管疾病等健康问题发展的风险因素。许多研究表明，维生素 D₃ 缺乏在 MetS 的发病机制中起作用。本研究旨在分析女性 MetS 与维生素 D₃ 水平之间的关系。实验室分析表明，只有 26.89%的参与者的维生素 D₃ 水平接近正常，腰臀比（WHR）测量显示 75.63%的女性存在男性型肥胖。处于经期的女性更常患有维生素 D₃ 缺乏症，而维生素 D₃ 水平升高的情况较少。结论如下：（1）维生素 D₃ 水平与 MetS 参数（即甘油三酯水平、低和高密度脂蛋白（LDL 和 HDL）水平、总胆固醇水平以及收缩压和舒张压（SBP 和 DBP））之间没有统计学上的显著关系。只有腹部肥胖的女性才会出现维生素 D 缺乏症。（2）低维生素 D₃ 水平是围绝经期妇女的典型特征。年龄是与维生素 D 相关的一个变量。（3）月经周期的存在是维生素 D 水平的一个重要影响因素。维生素 D 缺乏症在经期女性中更为常见。
