种族差异与产时 B 族链球菌定植：非裔美国女性的转化率更高。
Racial disparities in intrapartum group B Streptococcus colonization: a higher incidence of conversion in African American women.
机构信息
Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.
出版信息
J Perinatol. 2019 Mar;39(3):433-438. doi: 10.1038/s41372-018-0308-3. Epub 2019 Jan 11.
OBJECTIVE
To compare the incidence of group B Streptococcus (GBS) conversion from a negative antepartum to a positive intrapartum culture among women who self-identify as non-Hispanic black, Hispanic, or non-Hispanic white.
STUDY DESIGN
This was a prospective cohort study of women with a negative rectovaginal GBS culture obtained within 35 days of enrollment. An intrapartum rectovaginal swab was collected and cultured for GBS. Data were compared with chi-square, Fisher's exact, or Wilcoxon rank-sum test. Modified Poisson regression was used.
RESULTS
We enrolled 737 women; 75.4% were non-Hispanic white, 17.6% were non-Hispanic black, and 6.9% were Hispanic. Non-Hispanic black women were more likely to convert to GBS positive than non-Hispanic white women, 9.2% as compared to 5.3% (RR: 2.0; 95% CI: 1.02-3.8).
CONCLUSION
The increased incidence of positive intrapartum GBS cultures among non-Hispanic black women suggests that non-Hispanic black race is a risk factor for GBS conversion in the late third trimester.
目的
比较自我认定为非西班牙裔黑种人、西班牙裔或非西班牙裔白种人的女性中，从产前阴性到产时阳性的 B 组链球菌（GBS）转换发生率。
研究设计
这是一项前瞻性队列研究，纳入了在入组前 35 天内获得阴性直肠阴道 GBS 培养的女性。采集产时直肠阴道拭子进行 GBS 培养。采用卡方检验、Fisher 确切检验或 Wilcoxon 秩和检验进行数据比较。采用校正泊松回归。
结果
我们共纳入了 737 名女性；75.4%为非西班牙裔白种人，17.6%为非西班牙裔黑种人，6.9%为西班牙裔。与非西班牙裔白种人相比，非西班牙裔黑种人更有可能转为 GBS 阳性，分别为 9.2%和 5.3%（RR：2.0；95%CI：1.02-3.8）。
结论
非西班牙裔黑种人产时 GBS 阳性培养的发生率增加表明，非西班牙裔黑种人是妊娠晚期 GBS 转换的一个危险因素。
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