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《痴呆患者中使用阿拉伯版 Cornell 抑郁量表(A-CSDD)的适应和验证》。

The Adaptation and Validation of an Arabic Version of the Cornell Scale for Depression in Dementia (A-CSDD).

机构信息

Department of Psychology, Tunis Faculty of Humanities, Tunis University, Tunis, Tunisia.

Psychology Program, College of Arts and Sciences, Qatar University, Doha, Qatar.

出版信息

J Alzheimers Dis. 2019;67(3):839-848. doi: 10.3233/JAD-180448.

Abstract

BACKGROUND

Depression is a major disorder that can be ttriggering, exacerbating, or co-occurring with dementia symptoms. Its assessment is paramount to achieve diagnostic, prognostic, and therapeutic decisions. The Cornell Scale for Depression in Dementia (CSDD) is purposely designed to address clinically this issue.

OBJECTIVE

To examine the reliability and validity of an Arabic version of the CSDD (A-CSDD) in the Tunisian population.

METHODS

Fifty-seven participants took part in this study: 20 as a control group (NC), 18 as dementia patients with depression (DD), and 19 as depressed patients without dementia (DND); all patients met the DSM IV criteria for depression and/or dementia. A translated, back-translated and adapted Arabic version of the CSDD was administered in parallel with the Geriatric Depression Scale (GDS), the non-cognitive part of the Alzheimer's disease Assessment Scale, and the Mini-Mental State Examination.

RESULTS

The A-CSDD had good internal consistency (Cronbach's alpha = 0.85) and high test-retest reliability (Rho = 0.897, p < 0.001). The A-CSDD had excellent discriminatory power to diagnose depression in dementia patients (AUC = 0.90, p < 0.001) and good concurrent validity with the GDS (Rho = 0.70, p < 0.001). A principal component analysis with varimax rotation, performed on the DD group, led to a configuration of five factors explaining 75% of the variance.

CONCLUSIONS

The results showed that this Arabic-Tunisian version of the A-CSDD is reliable and valid for diagnosing depression in an elderly Tunisian population with dementia and can be used in clinical and research settings.

摘要

背景

抑郁症是一种主要的障碍,可能会引发、加重或与痴呆症状同时发生。对其进行评估对于做出诊断、预后和治疗决策至关重要。专为解决这一临床问题而设计的 Cornell 痴呆症抑郁量表(CSDD)。

目的

检验阿拉伯语版 CSDD(A-CSDD)在突尼斯人群中的信度和效度。

方法

共有 57 名参与者参加了这项研究:20 名作为对照组(NC),18 名作为患有抑郁症的痴呆症患者(DD),19 名作为没有痴呆症的抑郁症患者(DND);所有患者均符合 DSM-IV 抑郁症和/或痴呆症标准。CSDD 的翻译、回译和改编的阿拉伯语版本与老年抑郁量表(GDS)、阿尔茨海默病评估量表的非认知部分和简易精神状态检查同时进行。

结果

A-CSDD 具有良好的内部一致性(Cronbach's alpha=0.85)和高测试-重测信度(Rho=0.897,p<0.001)。A-CSDD 对诊断痴呆症患者的抑郁症具有出色的区分能力(AUC=0.90,p<0.001),并且与 GDS 具有良好的同时效度(Rho=0.70,p<0.001)。对 DD 组进行的主成分分析与方差极大旋转得出了一个由五个因素组成的配置,解释了 75%的方差。

结论

结果表明,这种阿拉伯语-突尼斯语版的 A-CSDD 可用于诊断患有痴呆症的老年突尼斯人群中的抑郁症,具有可靠性和有效性,可用于临床和研究环境。

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