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约旦安曼三级新生儿病房中用于新生儿呼吸窘迫的鼻塞式持续气道正压通气治疗:一项前瞻性观察研究

Bubble CPAP therapy for neonatal respiratory distress in level III neonatal unit in Amman, Jordan: a prospective observational study.

作者信息

Al-Lawama Manar, Alkhatib Haitham, Wakileh Zaid, Elqaisi Randa, AlMassad Ghada, Badran Eman, Hartman Tyler

机构信息

Pediatric Department, School of Medicine, Jordan University Hospital, The University of Jordan, Queen Rania Street, Amman 11942, Jordan,

Pediatric department, Geisel School of Medicine, Dartmouth University, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

出版信息

Int J Gen Med. 2018 Dec 24;12:25-30. doi: 10.2147/IJGM.S185264. eCollection 2019.

Abstract

PURPOSE

Bubble continuous positive airway pressure (bCPAP), a noninvasive respiratory support modality used to manage newborns with respiratory distress, provides continuous pressure that helps prevent derecruitment of alveoli, increasing the lungs' functional residual capacity, and thus decreasing the work of breathing. bCPAP can be used to manage various respiratory conditions in the newborn. In this prospective study, we describe our experience using bCPAP therapy as the primary respiratory support in a level III neonatal unit in Amman, Jordan. In addition to reporting therapeutic indications, durations, and side effects, we aimed to identify areas requiring improvement in bCPAP therapy in our population.

PATIENTS AND METHODS

This prospective observational study investigated the usage of bCPAP in the management of respiratory distress in newborns admitted to a Jordan University Hospital in Amman. The newborns were followed until discharge. The patients' demographic and clinical data were recorded.

RESULTS

A total of 143 babies (mean gestational age, 36±2.7 weeks; mean birth weight, 2,770±1,800 g) were included. All received bCPAP as the primary respiratory support. The most common underlying cause of respiratory distress was transient tachypnea of the newborn (42%), followed by prolonged respiratory transition (34%). The therapy success rate was 93.7%; only nine infants failed bCPAP. The most common side effect was physical facial injury.

CONCLUSION

The use of neonatal bCPAP therapy is well established in Jordan University Hospital. The area of potential improvement was the low rate of bCPAP use as a primary respiratory support in extremely premature infants.

摘要

目的

气泡持续气道正压通气(bCPAP)是一种用于治疗新生儿呼吸窘迫的无创呼吸支持方式,它提供持续压力,有助于防止肺泡萎陷,增加肺的功能残气量,从而减少呼吸功。bCPAP可用于治疗新生儿的各种呼吸疾病。在这项前瞻性研究中,我们描述了在约旦安曼一家三级新生儿病房将bCPAP治疗作为主要呼吸支持手段的经验。除了报告治疗指征、持续时间和副作用外,我们旨在确定我们人群中bCPAP治疗需要改进的方面。

患者与方法

这项前瞻性观察性研究调查了安曼约旦大学医院收治的新生儿使用bCPAP治疗呼吸窘迫的情况。对新生儿进行随访直至出院。记录患者的人口统计学和临床数据。

结果

共纳入143例婴儿(平均胎龄36±2.7周;平均出生体重2770±1800克)。所有婴儿均接受bCPAP作为主要呼吸支持。呼吸窘迫最常见的潜在原因是新生儿短暂性呼吸急促(42%),其次是呼吸过渡延长(34%)。治疗成功率为93.7%;只有9例婴儿bCPAP治疗失败。最常见的副作用是面部物理损伤。

结论

约旦大学医院使用新生儿bCPAP治疗已很成熟。潜在改进领域是极低出生体重儿将bCPAP作为主要呼吸支持的使用率较低。

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