Ayebare Elizabeth, Ntuyo Peter, Malande Oliver Ombeva, Nalwadda Gorrette
Department of Nursing, College of Health Sciences, Makerere University, Kampala, Uganda.
Department of Obstetrics and Gynaecology, Mulago Hospital, Kampala, Uganda.
Pan Afr Med J. 2018 Aug 10;30:272. doi: 10.11604/pamj.2018.30.272.13531. eCollection 2018.
Preterm birth, a leading cause of neonatal mortality accounts for 35 percent of all neonatal deaths worldwide. Uganda's high preterm birth rate of 13.6 per 1000 live births ranks 28 in the world. Efforts at reducing these pre-term births must entail interventions that target any associated risk factors. This study therefore aimed at identifying and describing the risk factors for preterm births among mothers delivering in Mulago Hospital.
This was a case control study among postpartum women in Mulago Hospital. Ninety nine women with preterm newborns were recruited as cases and 193 with full term babies were the controls. A semi-structured questionnaire was used to collect data. Data was entered into Epidata version 3.1 and exported to STATA 11 for univariate analysis and multivariate analysis by logistic regression.
Risk factors for preterm birth included maternal height less than 1.5 meters (OR 131.08 (20.35-844.02)), rural residence (OR 6.56(2.68-16.10)) and failure to attend antenatal care clinic (OR 8.88(1.44-54.67)). Pregnancy related risk factors included PPROM (OR 287.11(49.26-1673.28)), antepartum haemorrhage (OR 7.33(1.23-43.72)) and preeclampsia/eclampsia (OR 16.24(3.11-84.70)).
Preterm birth is more likely to occur in women of short stature, living in rural areas and those who do not attend antenatal care clinic. The preterm birth risk is higher for women who get PPROM, APH and preeclampsia/eclampsia in pregnancy. Early recognition and management of these high risk conditions among pregnant women may lead to a reduction in preterm birth rates.
早产是新生儿死亡的主要原因，占全球所有新生儿死亡的35%。乌干达的早产率很高，每1000例活产中有13.6例早产，在世界上排名第28位。降低这些早产率的努力必须包括针对任何相关风险因素的干预措施。因此，本研究旨在确定和描述在穆拉戈医院分娩的母亲中早产的风险因素。
这是一项在穆拉戈医院对产后妇女进行的病例对照研究。招募了99名早产新生儿的母亲作为病例，193名足月产婴儿的母亲作为对照。使用半结构化问卷收集数据。数据录入Epidata 3.1版本，并导出到STATA 11进行单因素分析和逻辑回归多因素分析。
早产的风险因素包括母亲身高低于1.5米（比值比131.08（20.35 - 844.02））、农村居住（比值比6.56（2.68 - 16.10））以及未参加产前保健门诊（比值比8.88（1.44 - 54.67））。与妊娠相关的风险因素包括胎膜早破（比值比287.11（49.26 - 1673.28））、产前出血（比值比7.33（1.23 - 43.72））和先兆子痫/子痫（比值比16.24（3.11 - 84.70））。
早产更有可能发生在身材矮小、居住在农村地区且未参加产前保健门诊的妇女中。在孕期发生胎膜早破、产前出血和先兆子痫/子痫的妇女早产风险更高。对孕妇中这些高危情况的早期识别和管理可能会降低早产率。
