与在埃塞俄比亚东南部锡达马地区公立医院分娩的母亲中早产相关的因素：病例对照研究。

Factors associated with preterm birth among mothers who gave birth at public Hospitals in Sidama regional state, Southeast Ethiopia: Unmatched case-control study.

机构信息

College of Medicine and Health Sciences, Mizan-Tepi University, Mizan Teferi, Ethiopia.

College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

出版信息

PLoS One. 2022 Apr 20;17(4):e0265594. doi: 10.1371/journal.pone.0265594. eCollection 2022.

DOI:10.1371/journal.pone.0265594

PMID:35442955

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9020679/

Abstract

BACKGROUND

Preterm birth remains the commonest cause of neonatal mortality, and morbidity representing one of the principal targets of neonatal health care. Ethiopia is one of the countries which shoulder the highest burden of preterm birth. Therefore, this study was aimed to assess factors associated with preterm birth at public hospitals in Sidama regional state.

METHODS

Facility-based case-control study was conducted at public hospitals in Sidama regional state, from 1st June to 1st September/2020. In this study, a total of 135 cases and 270 controls have participated. To recruit cases and controls consecutive sampling methods and simple random sampling techniques were used respectively. Data were collected using pretested structured interviewer-administered questionnaire, and checklist via chart review. Data were entered using EpiData version 3.1 and exported to SPSS version 20 for analysis. Independent variables with P-value < 0.25 in the bivariate logistic regression were candidates for multivariable logistic regression analysis. Finally, statistical significance was declared at P-value < 0.05.

RESULTS

The response rate was 100%. Rural resident (AOR = 2.034; 95%CI: 1.242, 3.331), no antenatal care service utilization (AOR = 2.516; 95%CI: 1.406, 4.503), pregnancy-induced hypertension (AOR = 2.870; 95%CI: 1.519, 5.424), chronic medical problem during pregnancy (AOR = 2.507; 95%CI: 1.345, 4.676), urinary tract infections (AOR = 3.023; 95%CI: 1.657, 5.513), birth space less than 2 years (AOR = 3.029; 95%CI: 1.484, 6.179), and physical intimate violence (AOR = 2.876; 95%CI: 1.534, 5.393) were significantly associated with preterm birth.

CONCLUSION

Most of the risk factors of preterm birth were found to be modifiable. Community mobilization on physical violence during pregnancy and antenatal care follow-up are the ground for the prevention of preterm birth because attentive and critical antenatal care screening practice could early identify risk factors. Besides, information communication education about preterm birth prevention was recommended.

摘要

背景

早产仍然是新生儿死亡的最常见原因，而发病率是新生儿保健的主要目标之一。埃塞俄比亚是早产儿负担最重的国家之一。因此，本研究旨在评估在锡达马地区州公立医院与早产相关的因素。

方法

2020 年 6 月 1 日至 9 月 1 日，在锡达马地区州的公立医院进行了一项基于设施的病例对照研究。在这项研究中，共有 135 例病例和 270 例对照参与。为了招募病例和对照，分别使用了连续抽样法和简单随机抽样技术。使用经过预测试的访谈员管理的问卷和检查表通过病历回顾收集数据。数据使用 EpiData 版本 3.1 录入，并导出到 SPSS 版本 20 进行分析。在双变量逻辑回归中 P 值<0.25 的自变量是多变量逻辑回归分析的候选者。最后，宣布 P 值<0.05 具有统计学意义。

结果

应答率为 100%。农村居民（AOR=2.034；95%CI：1.242，3.331）、未使用产前保健服务（AOR=2.516；95%CI：1.406，4.503）、妊娠高血压（AOR=2.870；95%CI：1.519，4.524）、怀孕期间存在慢性医疗问题（AOR=2.507；95%CI：1.345，4.676）、尿路感染（AOR=3.023；95%CI：1.657，5.513）、分娩间隔不到 2 年（AOR=3.029；95%CI：1.484，6.179）和身体亲密暴力（AOR=2.876；95%CI：1.534，5.393）与早产显著相关。