Nazarnezhad Mirzaali, Moosavy Seyed Hamid, Davoodian Parivash, Eftekhar Ebrahim, Nejatizadeh Abdolazim, Azad Mohsen
Infectious and Tropical Disease Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Hormozgan, Iran.
Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Hormozgan, Iran.
J Adv Pharm Technol Res. 2018 Oct-Dec;9(4):139-146. doi: 10.4103/japtr.JAPTR_328_18.
Considering the crucial importance of hepatitis B and its high prevalence in the society, the present study was conducted to examine the demographic and paraclinical characteristics of patients with chronic hepatitis B. This descriptive cross-sectional study examined 180 patients with hepatitis B presenting to Shahid Mohammadi Hospital and Clinic and other private clinics in Bandar Abbas, Iran, in 2016-17. The patients were divided into three main groups: chronic hepatitis, liver cirrhosis, and healthy carriers. Parametric and nonparametric tests were used to analyze the relationship between the quantitative variables in terms of their normal or nonnormal distribution ( < 0.05). About 13.5% of the patients had cirrhosis, 35.4% were healthy carriers, and 51.12% had chronic hepatitis. The number of male patients in the cirrhosis group and the number of female participants in the healthy carrier group were higher. The difference in gender distribution between the three groups was statistically significant. According to the results of this study, male and married people constitute a high percentage of the population of patients with chronic hepatitis B. The clinical symptoms of chronic hepatitis B often do not occur until the patient's progress to advanced stages and cirrhosis, and most of the population is asymptomatic. Contact with a person suspected to have hepatitis B is one of the major risk factors of this disease.
鉴于乙型肝炎的至关重要性及其在社会中的高流行率，本研究旨在调查慢性乙型肝炎患者的人口统计学和辅助临床特征。这项描述性横断面研究在2016 - 2017年期间对伊朗阿巴斯港的沙希德·穆罕默迪医院及诊所和其他私人诊所的180例乙型肝炎患者进行了检查。患者被分为三个主要组：慢性肝炎、肝硬化和健康携带者。根据定量变量的正态或非正态分布，使用参数和非参数检验分析它们之间的关系（<0.05）。约13.5%的患者患有肝硬化，35.4%为健康携带者，51.12%患有慢性肝炎。肝硬化组男性患者数量和健康携带者组女性参与者数量较多。三组之间的性别差异具有统计学意义。根据本研究结果，男性和已婚者在慢性乙型肝炎患者人群中占比很高。慢性乙型肝炎的临床症状通常直到患者进展到晚期和肝硬化阶段才会出现，而且大多数人群没有症状。与疑似患有乙型肝炎的人接触是该疾病的主要危险因素之一。
