教育对接受干扰素治疗患者生活质量的影响。
The effect of education on quality of life in patients under interferon therapy.
作者信息
Asadi Noghabi Ahmad Ali, Zandi Mitra, Mehran Abbas, Alavian Seyed Moayed, Dehkordi Ali Hasanpour
机构信息
School of Midwifery and Nursing, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Hepat Mon. 2010 Summer;10(3):218-22. Epub 2010 Sep 1.
BACKGROUND AND AIMS
The main purpose of treating and caring for patients with chronic viral hepatitis is to promote life satisfaction and a feeling of well-being in patients suffering from this disease. The aim of this study was to evaluate the effect of education on quality of life in patients with chronic hepatitis who were treated with Interferon alpha.
METHODS
This quasi-experimental study was conducted on 60 patients with viral hepatitis. The intervention included teaching them the method of self injection of Interferon alpha 2 b, giving them educational pamphlets and then following their continuing treatment with interferon. Patients were randomly assigned to two 30-patient groups. The data- gathering tool was a demographic characteristics questionnaire and the Quality of Life Questionnaire for Patients with Chronic Liver Disease (CLDQ). The educational program was done in four 45- minute sessions for the case group and their relatives. The follow-up period was 12 weeks. Quality of life in patients with chronic hepatitis was measured before initiating interferon therapy, and after the educational period. Quality of life in the two groups was compared.
RESULTS
The total quality of life score in the two groups before therapy did not show any significant difference (P = 0.351); while 12 weeks after education there was a significant difference between the two groups (P < 0.001) in three items including abdominal symptoms (P = 0.01), worry (P < 0.001) and emotional factors (P < 0.001). The other three items did not show a significant difference between the two groups. The total quality of life score in the case group was significantly different before and after education (P < 0.001), and improved after education. The total quality of life score in the control group did not differ significantly after 12 weeks (P = 0.143).
CONCLUSIONS
Planning short and simple educational programs has a significant effect on the patient's control of his/her disease and its side effects; and can improve quality of life, life satisfaction, and mechanisms of coping with treatment in patients with viral hepatitis.
背景与目的
治疗和护理慢性病毒性肝炎患者的主要目的是提高该疾病患者的生活满意度和幸福感。本研究的目的是评估教育对接受α干扰素治疗的慢性肝炎患者生活质量的影响。
方法
本准实验研究对60例病毒性肝炎患者进行。干预措施包括教授他们自行注射α干扰素2b的方法，给他们发放教育手册，然后跟踪他们继续使用干扰素治疗的情况。患者被随机分为两个各30人的组。数据收集工具是一份人口统计学特征问卷和慢性肝病患者生活质量问卷（CLDQ）。为病例组及其亲属开展了四个时长45分钟的教育课程。随访期为12周。在开始干扰素治疗前以及教育期结束后，对慢性肝炎患者的生活质量进行了测量。比较了两组的生活质量。
结果
治疗前两组的生活质量总分无显著差异（P = 0.351）；而教育12周后，两组在腹部症状（P = 0.01）、担忧（P < 0.001）和情绪因素（P < 0.001）这三个项目上存在显著差异（P < 0.001）。其他三个项目两组之间无显著差异。病例组教育前后生活质量总分有显著差异（P < 0.001），且教育后有所改善。对照组12周后的生活质量总分无显著差异（P = 0.143）。
结论
规划简短且简单的教育项目对患者控制疾病及其副作用有显著效果；并且可以提高病毒性肝炎患者的生活质量、生活满意度以及应对治疗的能力。
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