Department of Biotechnology, Hindusthan College of Arts and Science, Coimbatore 641 028, Tamil Nadu, India.
Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore 641 029, Tamil Nadu, India.
J Photochem Photobiol B. 2019 Feb;191:143-149. doi: 10.1016/j.jphotobiol.2018.12.026. Epub 2018 Dec 31.
Growing concerns over the toxicity of metallic nanoparticles synthesized using physical and chemical techniques seems to be a major hurdle for researchers. Green synthesis of nanoparticles is one of the promising, ecofriendly and safer methods. Utilizing plant sources as reducing agents will replace the use of toxic chemicals for nanoparticle synthesis. Among the various nanoparticles, copper has been theoretically and practically proved for its antimicrobial properties. However, to reduce the risk of copper toxicity, Ruellia tuberosa (R. tuberosa) aqueous extract is used for the synthesis of CuONPs in the present study. Nonetheless, till date no work has been reported on the use of R. tuberosa aqueous extract for the synthesis of CuONPs. In the present study, aqueous extract of R. tuberosa has been used for the synthesis of CuONPs. The synthesis of CuONPs was confirmed by the absorption peak at 327 nm representing the nanorods with an average size of 83.23 nm. Further, the CuONPs revealed antimicrobial effects against clinical pathogens such as Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae. Embedding CuONPs on cotton fabrics showed bactericidal activity against the bacterial pathogens. In addition, the photocatalytic property of the CuONPs was divulged by their crystal violet (CV) dye degradation potential. Thus, the green synthesized CuONPs using R. tuberosa could provide a remedy against bacterial pathogens in hospital and industrial environments.
人们越来越担心使用物理和化学技术合成的金属纳米粒子的毒性,这似乎是研究人员面临的一个主要障碍。纳米粒子的绿色合成是一种很有前途、环保和安全的方法。利用植物源作为还原剂将取代有毒化学物质用于纳米粒子合成。在各种纳米粒子中,铜已被理论和实践证明具有抗菌特性。然而,为了降低铜毒性的风险,在本研究中使用了 Ruellia tuberosa(R. tuberosa)的水提物来合成 CuONPs。尽管如此,迄今为止,尚未有关于使用 R. tuberosa 水提物合成 CuONPs 的报道。在本研究中,使用了 Ruellia tuberosa 的水提物来合成 CuONPs。CuONPs 的合成通过在 327nm 处的吸收峰得到证实,这代表了平均尺寸为 83.23nm 的纳米棒。此外,CuONPs 对金黄色葡萄球菌、大肠杆菌和肺炎克雷伯菌等临床病原体表现出抗菌作用。将 CuONPs 嵌入棉织物中显示出对细菌病原体的杀菌活性。此外,CuONPs 的光催化性能通过其结晶紫 (CV) 染料降解潜力得到揭示。因此,使用 Ruellia tuberosa 绿色合成的 CuONPs 可能为医院和工业环境中的细菌病原体提供一种治疗方法。