Department of Crop Science, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea.
Division of Life Sciences and Convergence Research Center for Insect Vectors, Incheon National University, Incheon 22012, Korea.
Molecules. 2019 Jan 11;24(2):258. doi: 10.3390/molecules24020258.
species are well recognized for their medicinal and aromatic properties. The comprehensive metabolite profiles of nine species have been determined. The extracts of these species were also screened for antioxidant and free radical scavenging activities. Forty-seven hydrophilic and seventeen lipophilic compounds were identified and quantified from the selected species. Also, eleven phenolic compounds, riboflavin and eight carotenoids were present, and their composition and content varied among the various species. The different species exhibited a range of antioxidant potencies. Horse mint especially exhibited the strongest antioxidant capacities (1,1-diphenyl-2-picryl-hydrazyl (DPPH), hydrogen peroxide, and reducing power assay) among the nine species. A difference between different samples from the same species was not observed by multivariate analysis. A high correlation between metabolites involved in closely linked biosynthetic pathways has been indicated. The projection to latent structure method, using the partial least squares (PLS) method, was applied to predict antioxidant capacities based on the metabolite profiles of leaves. According to the PLS analysis, several carotenoid contents, such as -β-carotene, 9-β-carotene, 13-β-carotene and lutein, as well as phenolic compounds, showed a positive relationship in reducing the power of extracts. Horse mint is a good candidate because of its high antioxidant efficacy among the nine species included in the study.
该属植物因其药用和芳香特性而广为人知。已经确定了 9 种该属植物的综合代谢产物图谱。还对这些种属植物的提取物进行了抗氧化和自由基清除活性筛选。从选定的种属中鉴定和定量了 47 种亲水性化合物和 17 种亲脂性化合物。此外，还存在 11 种酚类化合物、核黄素和 8 种类胡萝卜素，它们的组成和含量在不同的种属之间有所不同。不同的种属表现出不同的抗氧化能力。马薄荷在 9 种种属中表现出最强的抗氧化能力（1,1-二苯基-2-苦基肼（DPPH）、过氧化氢和还原力测定）。多元分析表明，同一物种的不同样本之间没有差异。已经表明，密切相关的生物合成途径中的代谢物之间存在高度相关性。使用偏最小二乘（PLS）方法的潜结构方法被应用于基于叶代谢产物图谱预测抗氧化能力。根据 PLS 分析，几种类胡萝卜素含量，如 -β-胡萝卜素、9-β-胡萝卜素、13-β-胡萝卜素和叶黄素，以及酚类化合物，在提取物的还原力方面表现出正相关关系。马薄荷是一个很好的候选物，因为它在研究中包括的 9 种种属植物中具有高抗氧化功效。
