Lambertini Martina, Vincenzi Colombina, Dika Emi, La Placa Michelangelo
Dermatology Division, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Skin Appendage Disord. 2018 Nov;5(1):42-45. doi: 10.1159/000488543. Epub 2018 May 3.
Chilblain lupus erythematosus is a rare, chronic variant of cutaneous lupus erythematosus that occurs during cold or damp periods on the hands, fingers, or feet. It is often associated with other forms of cutaneous lupus and about 20% of patients develop systemic lupus erythematosus. Various medications have been put forward, including steroids, mycophenolate mofetil, calcium channel blockers, and hydroxychloroquine, but the symptoms do not remit completely.
冻疮样红斑狼疮是一种罕见的慢性皮肤型红斑狼疮,发生于手部、手指或足部遇冷或潮湿时。它常与其他形式的皮肤型狼疮相关,约20%的患者会发展为系统性红斑狼疮。已提出多种药物治疗方案,包括类固醇、霉酚酸酯、钙通道阻滞剂和羟氯喹,但症状无法完全缓解。