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[金疮膏治疗难治性压疮的临床疗效]

[Clinical Effect of Treating Refractory Pressure Ulcers by Jinchuang Ointment].

作者信息

Dong Xing-Gang, Zhang Min, Feng Jian, Yu Zhi-Man, Guo Yuan, Xu Mei-Juan, Zhang Jing

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2017 Feb;37(2):155-159.

Abstract

Objective To observe the clinical effect of Jinchuang Ointment (JO) for treatment of refractory pressure ulcers. Methods Totally 306 patients with phase II , IIl, IV refractory pressure ul- cers were randomly assigned to the traditional Chinese herbal medicine ointment group, the JO group, the MepilexAg group,102 cases in each group. Each ulcer was scored using pressure ulcer scale for healing (PUSH) designed by National Pressure Ulcer Advisory Panel (NPUAP) before treatment, at day 7, 14, and 21 after treatment, respectively. The healing rate of pressure ulcer was observed at day 21. Results There was significant difference in PUSH score of the 3 groups between before treatment and at day 7/14)21 after treatment (P <0. 01). PUSH score was better in the JC group, as compared with that in the other two groups (P <0. 05) at day 14 and 21 after treatment. There was no significant difference in PUSH score between the traditional Chinese herbal medicine ointment group and the MepilexAg group (P >0. 05). Conclusions JO had significant effect in treatment of patients with phase II , III, IV pressure ulcers. The rate of wound healing at day 14/21 was significantly higher than that of traditional Chinese herbal medicine ointment and MepilexAg.

摘要

目的 观察金创膏治疗难治性压疮的临床效果。方法 将306例Ⅱ期、Ⅲ期、Ⅳ期难治性压疮患者随机分为中药膏剂组、金创膏组、美皮康银离子敷料组,每组102例。在治疗前、治疗后第7天、14天和21天,分别使用美国国家压疮咨询小组(NPUAP)设计的压疮愈合量表(PUSH)对每个溃疡进行评分。观察治疗第21天时压疮的愈合率。结果 治疗前与治疗后第7天/14天/21天,3组患者的PUSH评分差异有统计学意义(P<0.01)。治疗后第14天和21天,金创膏组的PUSH评分优于其他两组(P<0.05)。中药膏剂组与美皮康银离子敷料组的PUSH评分差异无统计学意义(P>0.05)。结论 金创膏治疗Ⅱ期、Ⅲ期、Ⅳ期压疮患者效果显著。治疗第14天/21天的伤口愈合率明显高于中药膏剂和美皮康银离子敷料。

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