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巴西针对一种目标消除疾病的成本:曼氏血吸虫病的案例。

The cost of a disease targeted for elimination in Brazil: the case of schistosomiasis mansoni.

作者信息

Nascimento Gilmara Lima, Pegado Helio Milani, Domingues Ana Lúcia Coutinho, Ximenes Ricardo Arraes de Alencar, Itria Alexander, Cruz Luciane Nascimento, Oliveira Maria Regina Fernandes de

机构信息

Universidade de Brasília, Núcleo de Medicina Tropical, Brasília, DF, Brasil.

Universidade Federal de Pernambuco, Recife, PE, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 2019 Jan 14;114:e180347. doi: 10.1590/0074-02760180347.

DOI:10.1590/0074-02760180347
PMID:30652735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6340134/
Abstract

BACKGROUND

Schistosomiasis mansoni is a poverty-related parasitic infection that has a variety of clinical manifestations. We consider the disability and deaths caused by schistosomiasis unacceptable for a tool-ready disease. Its condition in Brazil warrants an analysis that will enable better understanding of the local health losses and contribute to the complex decision-making process.

OBJECTIVE

This study estimates the cost of schistosomiasis in Brazil in 2015.

METHODS

We conducted a cost of illness study of schistosomiasis mansoni in Brazil in 2015 based on a prevalence approach and from a societal perspective. The study included 26,499 schistosomiasis carriers, 397 hepatosplenic cases, 48 cases with the neurological form, 284 hospitalisations, and 11,368.26 years of life lost (YLL) of which 5,187 years are attributable to economically active age groups.

RESULTS

The total cost of schistosomiasis mansoni in Brazil was estimated to be US$ 41,7million in 2015 with 94.61% of this being indirect costs.

CONCLUSIONS

The economic burden of schistosomiasis mansoni in Brazil is high and results in the loss of productivity. Its persistence in Brazil is a challenge to public health and requires inter-sectorial interventions in areas such as indoor water supply, basic sanitation, and education.

摘要

背景

曼氏血吸虫病是一种与贫困相关的寄生虫感染,有多种临床表现。对于一种已有应对手段的疾病而言,我们认为由血吸虫病导致的残疾和死亡是不可接受的。其在巴西的情况值得进行分析,以便更好地了解当地的健康损失,并为复杂的决策过程提供帮助。

目的

本研究估算了2015年巴西血吸虫病的成本。

方法

我们基于患病率方法并从社会角度对2015年巴西曼氏血吸虫病进行了疾病成本研究。该研究纳入了26499名血吸虫病携带者、397例肝脾型病例、48例神经型病例、284次住院治疗以及11368.26年的生命损失(YLL),其中5187年归因于经济活跃年龄组。

结果

2015年巴西曼氏血吸虫病的总成本估计为4170万美元,其中94.61%为间接成本。

结论

巴西曼氏血吸虫病的经济负担很高,并导致生产力损失。其在巴西的持续存在对公共卫生构成挑战,需要在室内供水、基本卫生设施和教育等领域进行跨部门干预。

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