Gao Hui, Xin Zhi-Ying, Yin Xin, Zhang Yu, Jin Qing-Long, Wen Xiao-Yu
Department of Hepatology, The First Hospital of Jilin University, Changchun.
Department of Gastroenterology, LaoLing People's Hospital, Laoling, China.
Medicine (Baltimore). 2019 Jan;98(3):e14116. doi: 10.1097/MD.0000000000014116.
Madelung disease (MD), a rarely reported disease, also known as benign symmetric lipomatosis, a disorder resulting from alcoholic abuse. It's largely under-recognized and under-reported, possibly because of unawareness of the condition by physicians.
A 45-year-old Chinese man presented with intermittent fatigue and abdominal distension and progressive bilateral breast enlargement. He has been a heavy drinker for ten years before onset of the disease with an average daily alcohol intake of more than 120 g/day.
Due to the patient's symptoms, laboratory test results, radiographic findings, he was diagnosed with MD.
We treated him with abstinence from alcohol and supportive therapy.
The patient is now in stable condition, with improvement in symptoms during follow-up.
Doctors, confronted with progressive bilateral breast enlargement in a patient with alcoholic liver disease, should be aware of the underreported MD. Recognition of this syndrome could help doctors establish diagnosis and emphasize the importance of alcohol abstinence as the mainstay of management.
马德隆病（MD）是一种罕见疾病，也被称为良性对称性脂肪瘤病，是一种由酒精滥用导致的病症。它很大程度上未得到充分认识和报告，可能是因为医生对该病症缺乏认知。
一名45岁的中国男性出现间歇性疲劳、腹胀以及双侧乳房进行性增大。在发病前他已酗酒十年，平均每日酒精摄入量超过120克/天。
根据患者症状、实验室检查结果及影像学检查结果，他被诊断为马德隆病。
我们对他采取戒酒及支持性治疗。
患者目前病情稳定，随访期间症状有所改善。
面对患有酒精性肝病且出现双侧乳房进行性增大的患者，医生应意识到未得到充分报告的马德隆病。认识到该综合征有助于医生进行诊断，并强调戒酒作为主要治疗手段的重要性。
