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Madelung 病病例报告及文献综述

A case report on Madelung's disease and comprehensive review of the literature.

机构信息

Department of General surgery, Bethune International Peace Hospital, No. 398, Zhongshan West Road, Qiaoxi District, Shijiazhuang, 050051, Hebei Province, China.

出版信息

Orphanet J Rare Dis. 2024 Aug 17;19(1):302. doi: 10.1186/s13023-024-03303-w.

Abstract

BACKGROUND

Madelung's disease (MD), alternatively referred to as benign symmetric lipomatosis, multiple symmetric lipomatosis, or Launois-Bensaude syndrome, is an uncommon benign disorder marked by symmetric proliferation of adipose tissue in the head, neck, and torso regions.

CASE DESCRIPTION

In this case, the patient was a female with the late middle-aged demographic, diagnosed with Type I MD. Notably, she exhibited no prior history of alcohol consumption, and there was no family history of MD. Subsequent to the clinical diagnosis, the patient underwent medical imaging assessments to delineate the surgical parameters. Post-surgery, she demonstrated a favorable recovery trajectory, marked by the absence of any surgical complications.

RESULT

The patient underwent successful surgical excision of the lipomatous mass. Postoperatively, she had an uneventful recovery with no complications and no recurrence observed during the follow-up period of seven months.

CONCLUSION

Timely diagnosis and early surgical intervention play a pivotal role in enhancing the quality of life for individuals with MD. Preoperative medical imaging examinations function as highly effective tools, contributing to heightened surgical safety and a decreased probability of encountering complications during the surgical procedure.

摘要

背景

Madelung 病(MD),也称为良性对称性脂肪瘤病、多发性对称性脂肪瘤病或 Launois-Bensaude 综合征,是一种罕见的良性疾病,其特征是头部、颈部和躯干区域的脂肪组织对称增生。

病例描述

本例患者为女性,年龄处于中年后期,诊断为 1 型 MD。值得注意的是,她没有饮酒史,也没有 MD 的家族史。在临床诊断后,对患者进行了医学影像学评估以划定手术参数。手术后,她的恢复情况良好,没有出现任何手术并发症。

结果

患者成功接受了脂肪瘤肿块的手术切除。术后,她恢复顺利,没有并发症,在七个月的随访期间没有复发。

结论

及时诊断和早期手术干预对改善 MD 患者的生活质量至关重要。术前医学影像学检查是一种非常有效的工具,可以提高手术安全性,降低手术过程中发生并发症的概率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a7/11330121/ce9d48e28907/13023_2024_3303_Fig1_HTML.jpg

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