From the Stem Cell Institute, James Graham Brown Cancer Center, University of Louisville, KY (M.Z.R., J.R., M.K.).
Department of Regenerative Medicine, and Center for Preclinical Research and Technology at Warsaw Medical University, Poland (M.Z.R., M.K.).
Circ Res. 2019 Jan 18;124(2):208-210. doi: 10.1161/CIRCRESAHA.118.314287.
Results from at least 20 independent laboratories indicate that adult tissues contain rare, early-development stem cells known as very small embryonic-like stem cells (VSELs), which can differentiate into cells from more than one germ layer. Further research on these cells may provide a path forward to application of these cells in regenerative medicine that perhaps may solve several problems inherent in the use of controversial embryonic stem cells (ESCs) and somehow problematic induced pluripotent stem cells (iPSCs).
至少 20 个独立实验室的结果表明，成人组织中含有罕见的早期发育干细胞，称为非常小的胚胎样干细胞（VSELs），它们可以分化为来自多个胚层的细胞。对这些细胞的进一步研究可能为这些细胞在再生医学中的应用提供一条途径，也许可以解决使用有争议的胚胎干细胞（ESCs）和某些有问题的诱导多能干细胞（iPSCs）所固有的几个问题。
