Mistretta Francesco A, Carrion Diego M, Nazzani Sebastiano, Vásquez Juan L, Fiori Cristian, De Cobelli Ottavio, Porpiglia Francesco, Esperto Francesco
Department of Urology, European Institute of Oncology, Milan, Italy -
European Society of Residents in Urology (ESRU), Brussels, Belgium -
Minerva Urol Nefrol. 2019 Jun;71(3):191-200. doi: 10.23736/S0393-2249.19.03311-3. Epub 2019 Jan 17.
Upper tract urinary carcinoma (UTUC) and bladder cancer (BCa) share similar biological, histological and pathological characteristics. These resemblances could explain the high rate of synchronous and metachronous tumors affecting both upper urinary tract and bladder. In patients affected by primary UTUC bladder recurrence is quite common and it represents one of the major concerns during the follow-up of patients who underwent radical nephroureterectomy. Conversely, UTUC recurrence after primary non-muscular invasive BCa is a relatively rare event. Moreover, there is no clear evidence on whether the use of Double-J stenting as drainage in patients affected by BCa increases the risk of UTUC recurrence. The aim of the current study was to summarize the most recent evidence regarding the bladder recurrence after UTUC surgical treatment, and the UTUC recurrence after stent positioning in patients affected by primary BCa.
上尿路尿路上皮癌（UTUC）和膀胱癌（BCa）具有相似的生物学、组织学和病理学特征。这些相似之处可以解释上尿路和膀胱同时性及异时性肿瘤的高发病率。在原发性UTUC患者中，膀胱复发相当常见，这是接受根治性肾输尿管切除术患者随访期间的主要担忧之一。相反，原发性非肌层浸润性BCa后UTUC复发是相对罕见的事件。此外，对于BCa患者使用双J支架作为引流是否会增加UTUC复发风险，尚无明确证据。本研究的目的是总结关于UTUC手术治疗后膀胱复发以及原发性BCa患者支架置入后UTUC复发的最新证据。
