Waxman D
J R Soc Med. 1988 Dec;81(12):718-20. doi: 10.1177/014107688808101212.
The irritable bowel syndrome is discussed together with some of its theories, methods of investigation and various treatment regimens. Eight case histories are reported. In each patient, symptoms appeared to be precipitated by situations interpreted by that patient as stressful. A programme of prospective desensitization using hypnosis is described. Where symptoms of depression were additionally present, antidepressant medication was prescribed. This was subsequently phased out as and when indicated. Where patients had been taking antidiarrhoeal or antispasmodic drugs, various stool bulking agents or benzodiazepines, these were also slowly discontinued as treatment progressed. Cases were followed up from 3 months to 12 years. In 2 cases recurrence of symptoms was again successfully treated. There was no recurrence of any of the bowel symptoms in any other patient. The results support the view that the irritable bowel syndrome is psychogenic in origin.
本文讨论了肠易激综合征及其相关理论、研究方法和各种治疗方案。报告了8个病例。在每个患者中，症状似乎都是由患者认为有压力的情况引发的。描述了一种使用催眠进行前瞻性脱敏的方案。如果患者还伴有抑郁症状，则开具抗抑郁药物。随后根据指示逐步停用该药物。如果患者一直在服用止泻药、解痉药、各种大便膨松剂或苯二氮䓬类药物，随着治疗的进展，这些药物也会慢慢停用。对病例进行了3个月至12年的随访。2例症状复发再次得到成功治疗。其他患者均未出现任何肠道症状复发。这些结果支持肠易激综合征起源于心理因素的观点。
