Scotelaro-Alves Hugo Guimarães, Fernandes Nurimar Conceição, Ramos-E-Silva Marcia
Sector of Dermatology, Post-Graduation Program in Medical Clinics, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil,
Sector of Dermatology and Institute of Pediatrics, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Clin Cosmet Investig Dermatol. 2019 Jan 3;12:23-28. doi: 10.2147/CCID.S150778. eCollection 2019.
Previously known as dyshidrosis, recurrent vesicular palmoplantar dermatitis (RVPD) is presented as severe eruption of nonerythematous, symmetrical vesicles or bullae located along the lateral sides of fingers, on the palmar or plantar areas, and developing into a chronic and recurrent condition. Although very frequently observed on the hands, there are no specific studies about such eczema in children and adolescents.
To report on the RVPD clinical profile in children and adolescents, and monitor the association of RVPD with seasonal variations, hyperhidrosis, atopy and nickel sulfate.
Eighteen patients affected by RVPD were submitted to clinical and laboratory assessment through anamnesis, physical exam, mycological exam, patch test, complete blood count and serum IgE levels.
Seven patients (38.9%) reported increased frequency of eruptions during the summer months; 12 patients (66.7%) presented hyperhidrosis; in 14 cases (77.8%), atopic factors were determined; reaction to nickel sulfate was positive in three patients (16.7%).
RVPD onset may occur at an early age, developing into a chronic and recurrent infection. Hyperhidrosis and atopic status was established in the clinical profile and no connection between nickel sulfate and RVPD was observed.
复发性水疱性掌跖皮炎(RVPD)以前称为汗疱疹,表现为沿手指侧面、手掌或足底区域出现严重的非红斑性、对称性水疱或大疱,并发展为慢性复发性疾病。虽然在手部非常常见,但关于儿童和青少年此类湿疹尚无具体研究。
报告儿童和青少年RVPD的临床特征,并监测RVPD与季节变化、多汗症、特应性和硫酸镍的关联。
18例RVPD患者通过病史采集、体格检查、真菌学检查、斑贴试验、全血细胞计数和血清IgE水平进行临床和实验室评估。
7例患者(38.9%)报告夏季发作频率增加;12例患者(66.7%)有多汗症;14例(77.8%)确定有特应性因素;3例患者(16.7%)对硫酸镍反应呈阳性。
RVPD可能在早年发病,发展为慢性复发性感染。多汗症和特应性状态在临床特征中得到证实,未观察到硫酸镍与RVPD之间的关联。