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不同唾液分泌减少测试下口干指数、临床口腔干燥量表与ESSPRI之间的相关性。

Correlation between Xerostomia index, Clinical Oral Dryness Scale, and ESSPRI with different hyposalivation tests.

作者信息

Hijjaw Ola, Alawneh Mohammad, Ojjoh Khaled, Abuasbeh Hazem, Alkilany Ahmad, Qasem Nabeel, Al-Essa Mohammad, AlRyalat Saif Aldeen

机构信息

Department of Internal Medicine, The University of Jordan, Amman 11942, Jordan.

Department of Ophthalmology, The University of Jordan, Amman 11942, Jordan,

出版信息

Open Access Rheumatol. 2019 Jan 4;11:11-18. doi: 10.2147/OARRR.S188937. eCollection 2019.

DOI:10.2147/OARRR.S188937
PMID:30655709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6324613/
Abstract

BACKGROUND AND OBJECTIVE

Xerostomia is a subjective measure of dry mouth, while hyposalivation is an objective measure of reduced saliva flow rate. In this study, we aim to assess the association between commonly used xerostomia scoring systems, with different hyposalivation measures among Sjogren Syndrome (SS) patients.

METHODS

In a cohort of SS patients, we assessed xerostomia using Xerostomia index, clinical oral dryness scale (CODS), and the European League Against Rheumatism SS Patient-Reported Index (ESSPRI), and we assessed hyposalivation using unstimulated whole saliva flow (UWS), stimulated whole saliva flow (SWS), and stimulated parotid flow (SPF). We analyzed the association between xerostomia and hyposalivation using association tests in SPSS.

RESULTS

We included a total of 49 patients in this study, of which 34 (68%) had primary SS, and 15 (32%) had secondary. CODS was significantly correlated with SWS (=0.048), with a negative correlation coefficient of 0.216, and with SPF (=0.009), with a negative correlation coefficient of 0.291. The dryness domain of ESSPRI was significantly correlated with UWS (=0.031) with a negative correlation coefficient of 0.233.

CONCLUSION

CODS is the scoring system with the highest correlation with hyposalivation, particularly SWS and SPF, followed by ESSPRI dry domain, which is correlated with UWS. Xerostomia index is not correlated with hyposalivation.

摘要

背景与目的

口干症是对口腔干燥的主观衡量，而唾液分泌减少是唾液流速降低的客观衡量。在本研究中，我们旨在评估干燥综合征（SS）患者中常用的口干症评分系统与不同唾液分泌减少指标之间的关联。

方法

在一组SS患者中，我们使用口干症指数、临床口腔干燥量表（CODS）和欧洲抗风湿病联盟SS患者报告指数（ESSPRI）评估口干症，使用非刺激性全唾液流速（UWS）、刺激性全唾液流速（SWS）和刺激性腮腺流速（SPF）评估唾液分泌减少情况。我们在SPSS中使用关联检验分析口干症与唾液分泌减少之间的关联。

结果

本研究共纳入49例患者，其中34例（68%）为原发性SS，15例（32%）为继发性。CODS与SWS显著相关（=0.048），相关系数为-0.216，与SPF显著相关（=0.009），相关系数为-0.291。ESSPRI的干燥领域与UWS显著相关（=0.031），相关系数为-0.233。

结论

CODS是与唾液分泌减少相关性最高的评分系统，尤其是与SWS和SPF，其次是与UWS相关的ESSPRI干燥领域。口干症指数与唾液分泌减少无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/8e9abbc6a633/oarrr-11-011Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/03be4cdfce6c/oarrr-11-011Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/d773382add3c/oarrr-11-011Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/1f990d052d7e/oarrr-11-011Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/8e9abbc6a633/oarrr-11-011Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/03be4cdfce6c/oarrr-11-011Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/d773382add3c/oarrr-11-011Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/1f990d052d7e/oarrr-11-011Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef66/6324613/8e9abbc6a633/oarrr-11-011Fig4.jpg

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