Buehring G C
School of Public Health, University of California, Berkeley 94720.
Biomed Pharmacother. 1988;42(8):525-30.
This article reviews 20 years of research to determine if oral contraceptive usage increases the risk of breast cancer. Studies using animal models, epidemiology, and human tissues are presented. Results suggest oral contraceptives do not initiate breast cancer, but may act as tumor promoters, stimulating the growth of already transformed cells. The answers are not all in, and the need for continued research is emphasized.
本文回顾了20年的研究，以确定口服避孕药的使用是否会增加患乳腺癌的风险。文中呈现了使用动物模型、流行病学和人体组织进行的研究。结果表明，口服避孕药不会引发乳腺癌，但可能起到肿瘤促进剂的作用，刺激已转化细胞的生长。答案尚未完全明确，文中强调了持续研究的必要性。
