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Recurrent High-Risk Pulmonary Thromboembolism Treated with Repeated Thrombolytic Therapy Could be Helpful for Certain Patients: A Case Report and Review of the Literature.重复溶栓治疗复发性高危肺血栓栓塞症可能对某些患者有益:一例病例报告及文献复习
Eur J Case Rep Intern Med. 2023 Aug 25;10(9):004042. doi: 10.12890/2023_004042. eCollection 2023.

本文引用的文献

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Risk-adapted management of pulmonary embolism.肺栓塞的风险适应性管理。
Thromb Res. 2017 Mar;151 Suppl 1:S92-S96. doi: 10.1016/S0049-3848(17)30076-2.
2
Systemic Thrombolysis for Pulmonary Embolism: A Review.肺栓塞的全身溶栓治疗:综述
P T. 2016 Dec;41(12):770-775.
3
Management of Pulmonary Embolism: An Update.肺栓塞的管理:最新进展。
J Am Coll Cardiol. 2016 Mar 1;67(8):976-990. doi: 10.1016/j.jacc.2015.11.061.
4
Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report.抗栓治疗 VTE 疾病:CHEST 指南和专家小组报告。
Chest. 2016 Feb;149(2):315-352. doi: 10.1016/j.chest.2015.11.026. Epub 2016 Jan 7.
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Guidance for the use of thrombolytic therapy for the treatment of venous thromboembolism.静脉血栓栓塞症溶栓治疗的使用指南。
J Thromb Thrombolysis. 2016 Jan;41(1):68-80. doi: 10.1007/s11239-015-1318-z.
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Pulmonary embolism: Epidemiology and registries.肺栓塞:流行病学与登记处
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Thrombolytic therapy for pulmonary embolism.肺栓塞的溶栓治疗
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8
Systemic thrombolysis for acute pulmonary embolism.急性肺栓塞的全身溶栓治疗。
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9
Thrombosis: a major contributor to global disease burden.血栓形成:全球疾病负担的主要促成因素。
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10
2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism.2014年欧洲心脏病学会急性肺栓塞诊断和管理指南
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复发性肺血栓栓塞症的重复溶栓治疗:2例报告及文献复习

Repeated Thrombolytic Treatment for Recurrent Pulmonary Thromboembolism: A Report of 2 Cases and a Literature Review.

作者信息

Argüder Emine, Parlak Ebru, Hezer Habibe, Karalezli Ayşegül, Hasanoğlu H Canan

机构信息

Department of Chest Diseases, Ankara Yıldırım Beyazıt University School of Medicine, Ankara, Turkey.

Clinic of Chest Diseases, Ankara Atatürk Training and Research Hospital, Ankara, Turkey.

出版信息

Turk Thorac J. 2019 Jan 1;20(1):61-65. doi: 10.5152/TurkThoracJ.2018.18020.

DOI:10.5152/TurkThoracJ.2018.18020
PMID:30664427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6340683/
Abstract

We present 2 cases of pulmonary thromboembolism (PTE). The first case, a 50-year-old man, was admitted to the emergency department because of sudden onset dyspnea and left side chest pain. He was diagnosed with intermediate-risk (submassive) PTE, and thrombolytic treatment was commenced. The patient fully recovered, but 5 days later, he was diagnosed with a new, high-risk PTE. The second patient, a 23-year-old woman, presented with syncope, dyspnea, and chest pain for 2 days. She was diagnosed with high-risk (massive) PTE. Thrombolytic treatment was commenced, and the patient fully recovered, too. But the later patient was also diagnosed with a new PTE 4 days later. We applied repeated thrombolytic treatment in the patients due to repeated PTE. The first patient fully recovered and was discharged from the hospital, but the second patient died because of gastrointestinal bleeding and renal insufficiency. A repeated thrombolytic treatment could be an alternative treatment for these patients, considering treatment's risks.

摘要

我们报告2例肺血栓栓塞症(PTE)。第一例,一名50岁男性,因突发呼吸困难和左侧胸痛被收入急诊科。他被诊断为中危(次大面积)PTE,并开始进行溶栓治疗。患者完全康复,但5天后,他又被诊断为新的高危PTE。第二例患者,一名23岁女性,出现晕厥、呼吸困难和胸痛2天。她被诊断为高危(大面积)PTE。开始进行溶栓治疗,患者也完全康复。但该患者在4天后也被诊断为新的PTE。由于PTE复发,我们对患者应用了重复溶栓治疗。第一名患者完全康复并出院,但第二名患者因胃肠道出血和肾功能不全死亡。考虑到治疗风险,重复溶栓治疗可能是这些患者的一种替代治疗方法。