M.Sc. in Nutrition, Preventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
Assistant Professor (PhD) of Nutrition, Department of Clinical Nutrition & Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Complement Ther Med. 2019 Feb;42:137-144. doi: 10.1016/j.ctim.2018.11.013. Epub 2018 Nov 12.
The aim of this systematic review was to assess the effects of Spirulina supplementation on metabolic syndrome components, its liver manifestation and related inflammatory markers.
We searched PubMed and Scopus (up to August 2017) to identify relevant studies. English randomized controlled trials (RCTs) investigating the effects of Spirulina supplementation on factors associated with metabolic syndrome in human models, were included in the review.
Among 720 articles related to Spirulina in the primary search, 22 of them were eligible human RCTs and finally 18 of them were included in the review. The systematic review revealed that oral dosage range of 1-19gr/day for 0.5-6 months of Spirulina supplementation have positive effects on metabolic syndrome components.
Spirulina can be possibly administered as a safe and efficient supplementation in the case of metabolic syndrome components, although determining the optimal dosage and period of supplementation still needs further investigations.
本系统评价旨在评估螺旋藻补充剂对代谢综合征成分、肝脏表现和相关炎症标志物的影响。
我们检索了 PubMed 和 Scopus（截至 2017 年 8 月）以确定相关研究。本综述纳入了评估螺旋藻补充剂对人类模型中与代谢综合征相关因素影响的英文随机对照试验（RCT）。
在初步检索中与螺旋藻相关的 720 篇文章中，有 22 项是符合条件的人类 RCT，最终有 18 项被纳入综述。系统评价显示，口服剂量为 1-19 克/天，持续 0.5-6 个月的螺旋藻补充剂对代谢综合征成分有积极影响。
尽管确定最佳剂量和补充期限仍需要进一步研究，但在代谢综合征成分的情况下，螺旋藻可作为一种安全有效的补充剂使用。
