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作为术后伤口感染对标准经验性抗菌治疗耐药的罕见原因。

as a Rare Cause of Postoperative Wound Infection Resistant to Standard Empiric Antimicrobial Therapy.

作者信息

Gaffar Sheema, Birknes John K, Cunnion Kenji M

机构信息

Department of Pediatrics, Eastern Virginia Medical School, 700 West Olney Road, Norfolk, VA 23507, USA.

Division of Pediatric Neurosurgery, Children's Hospital of the King's Daughters, 601 Children's Lane, Norfolk, VA 23507, USA.

出版信息

Case Rep Pediatr. 2018 Dec 20;2018:3483685. doi: 10.1155/2018/3483685. eCollection 2018.

DOI:10.1155/2018/3483685
PMID:30671272
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6317086/
Abstract

Fungal infections are rare causes of acute surgical wound infections, but is not an infrequent etiology in chronic wound infections. species is a common cause of tinea capitis but has not been reported as a cause of neurosurgical wound infection. We report a case of causing a nonhealing surgical wound infection in a 14-year-old male after hemicraniectomy. His wound infection was notable for production of purulent exudate from the wound and lack of clinical improvement despite empiric treatment with multiple broad-spectrum antibiotics targeting typical bacterial causes of wound infection. Multiple wound cultures consistently grew fungus, and his wound infection clinically improved rapidly after starting terbinafine and discontinuing antibiotics.

摘要

真菌感染是急性外科伤口感染的罕见原因,但在慢性伤口感染中并非不常见的病因。某菌种是头癣的常见病因,但尚未有作为神经外科伤口感染病因的报道。我们报告一例该菌种在一名14岁男性颅骨切除术后导致手术伤口不愈合感染的病例。他的伤口感染表现为伤口有脓性渗出物,尽管针对伤口感染的典型细菌病因经验性使用了多种广谱抗生素治疗,但临床症状并无改善。多次伤口培养均持续培养出该真菌,在开始使用特比萘芬并停用抗生素后,他的伤口感染临床症状迅速改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215c/6317086/0cccf943f360/CRIPE2018-3483685.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215c/6317086/0cccf943f360/CRIPE2018-3483685.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215c/6317086/0cccf943f360/CRIPE2018-3483685.001.jpg

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