Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Department of Vitreoretina, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Indian J Ophthalmol. 2019 Feb;67(2):247-251. doi: 10.4103/ijo.IJO_831_18.
To evaluate clinical profile of patients with uveitis who developed central serous chorioretinopathy (CSC).
Retrospective case series of consecutive patients of uveitis with CSC managed at a tertiary eye care center in India between 1994 and 2014. The data about clinical features, investigations, treatment, and outcomes were obtained from their medical records.
A total of 31 eyes of 26 patients with uveitis with a diagnosis of CSC between June 1994 and May 2014 were included in the study. The mean age of presentation was 42.8 ± 9.2 years, and 88.4% of the patients were male. CSC was bilateral in 19.2% of the patients, and in 38.4% patients uveitis was because of infectious etiology. CSC developed in 23 (88.5%) patients when they were on oral corticosteroid. The most common cause of uveitis in our study was choroiditis (48.4%), followed by retinal vasculitis (12.9%). The mean time for resolution of CSC was relatively less in patients with uveitis because of infectious etiology. In 10% eyes vision remained the same and deterioration of vision was noted in 19% eyes. Best corrected visual acuity of the patients at the time of presentation with CSC was 0.56 ± 0.34 and after the resolution of CSC was 0.48 ± 0.5 (P < 0.0005).
Patients with choroidal inflammations are more prone to develop CSC compared with other subtypes of uveitis. Management of CSC in uveitis can be challenging.
评估发生中心性浆液性脉络膜视网膜病变（CSC）的葡萄膜炎患者的临床特征。
本研究为回顾性连续病例系列研究，纳入了 1994 年至 2014 年期间在印度一家三级眼科中心接受治疗的葡萄膜炎合并 CSC 患者。从病历中获取了有关临床特征、检查、治疗和结局的数据。
研究共纳入了 31 只眼（26 例患者），这些患者均于 1994 年 6 月至 2014 年 5 月间被诊断为葡萄膜炎合并 CSC。发病时的平均年龄为 42.8±9.2 岁，88.4%的患者为男性。19.2%的患者 CSC 为双侧性，38.4%的患者葡萄膜炎病因是感染性的。23 例（88.5%）患者在口服皮质类固醇时发生 CSC。本研究中最常见的葡萄膜炎病因是脉络膜炎（48.4%），其次是视网膜血管炎（12.9%）。葡萄膜炎病因是感染性的患者的 CSC 缓解时间相对较短。10%的眼视力保持不变，19%的眼视力恶化。发生 CSC 时患者的最佳矫正视力为 0.56±0.34，CSC 缓解后的最佳矫正视力为 0.48±0.5（P<0.0005）。
与其他类型的葡萄膜炎相比，葡萄膜炎症患者更易发生 CSC。葡萄膜炎合并 CSC 的治疗可能具有挑战性。
