Klawonn Anna M, Malenka Robert C
Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University School of Medicine, Stanford, California 94305, USA.
Cold Spring Harb Symp Quant Biol. 2018;83:119-129. doi: 10.1101/sqb.2018.83.037457. Epub 2019 Jan 23.
The nucleus accumbens (NAc) is a key node of the brain's circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inputs that influence NAc activity in complex ways that are still poorly understood. Here, we briefly review current knowledge about the behavioral consequences of NAc modulation, focusing on recent studies that use novel techniques developed and implemented over the last decade.
伏隔核（NAc）是大脑回路的一个关键节点，负责将动机转化为行动。几乎在所有形式的适应性和病理性动机行为中，它都被认为起着关键作用。它受到大量输入的调节，这些输入以复杂的方式影响NAc的活动，而我们对这些方式仍知之甚少。在这里，我们简要回顾一下关于NAc调节行为后果的现有知识，重点关注过去十年中开发和应用的新技术的最新研究。
