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野生香蕉[芭蕉属超大型植物(罗克斯堡)奇斯曼]:民族医学、植物化学和药理学概述。

Wild banana [Ensete superbum (Roxb.) Cheesman.]: Ethnomedicinal, phytochemical and pharmacological overview.

机构信息

National Innovation Foundation-India (Autonomous Body of Department of Science and Technology, Govt. of India), Grambharti, Amarapur, Gandhinagar, Gujarat 382650, India.

National Innovation Foundation-India (Autonomous Body of Department of Science and Technology, Govt. of India), Grambharti, Amarapur, Gandhinagar, Gujarat 382650, India.

出版信息

J Ethnopharmacol. 2019 Apr 6;233:218-233. doi: 10.1016/j.jep.2018.12.048. Epub 2019 Jan 25.

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Ensete superbum (Roxb.) Cheesman. (Family: Musaceae), commonly known as "Wild Banana" is well recorded as popular ethnomedicine for medicinal and nutritional uses by different people and communities native to India, Ethiopia, Thailand, Myanmar and Vietnam.

AIM OF THE REVIEW

Despite the wide ethnomedicinal and pharmacological studies on E. superbum, there are no concise elaborated article comprising reviews of published literature. So, herein we designed this review article to discuss the current ethnopharmacology, pharmacognosy, phytochemistry, pharmacology and intellectual property status of E. superbum.

MATERIALS AND METHODS

Exhaustive literature searches were performed on E. superbum through various scientific and patent search engines such as Google Scholar, Scopus, PubMed, USPTO, Google patents, and Espacenet, using different keywords for screening of relevant information.

RESULTS

E. superbum was recorded in different regions of the world for ailments such as dog bite, calculi, semen production, abortion, leucorrhoea, stomachache, immune response, pain, diabetes, psychosomatic, contraceptive, umbilical cord care, convulsions, pneumonia, cholera, labor and delivery pain, dehydration, appendicitis, chickenpox, measles, urinary problems, food poisoning, snake bites, diarrhoea, dysentery, jaundice, bone fracture, infections, fever, asthma, hiccups and leucoderma. Major bioactive phytochemicals such as triterpenoid esters, proanthocyanidin, pro-pelargonidin glucosides, pelargonidin, anigorufone, hydroxyanigorufone, β-carboline alkaloids and fractions such as VIDR-2T, VIDR-2GC, VIDR-2GD were reported. Pharmacologically, E. superbum was found to be non-toxic (LD = 3235.9 mg/kg) and has been reported to possesses antiurolithiatic, antidiabetic, antifertility, anti-estrogenic, antiviral, cardiovascular and anti-inflammatory activities.

CONCLUSIONS

E. superbum could be an excellent source of safe and effective medicinal and nutritional herbal remedies for human and animal consumption.

摘要

民族药理学相关性

芭蕉芋(Roxb.)Cheesman。(科:芭蕉科),俗称“野香蕉”,在印度、埃塞俄比亚、泰国、缅甸和越南等地,不同人群和社区将其作为流行的民族药物,广泛用于药用和营养用途,有相关记载。

目的

尽管芭蕉芋有广泛的民族医学和药理学研究,但没有简洁的综合文献综述文章。因此,本文旨在讨论芭蕉芋的当前民族药理学、生药学、植物化学、药理学和知识产权状况。

材料和方法

通过各种科学和专利搜索引擎,如 Google Scholar、Scopus、PubMed、USPTO、Google 专利和 Espacenet,对芭蕉芋进行了全面的文献检索,使用不同的关键词筛选相关信息。

结果

芭蕉芋在世界不同地区被记录用于治疗狗咬伤、结石、精液生产、堕胎、白带、胃痛、免疫反应、疼痛、糖尿病、身心、避孕药、脐带护理、惊厥、肺炎、霍乱、分娩疼痛、脱水、阑尾炎、水痘、麻疹、尿问题、食物中毒、蛇咬伤、腹泻、痢疾、黄疸、骨折、感染、发烧、哮喘、打嗝和白癜风等疾病。报告了主要的生物活性植物化学物质,如三萜酯、原花青素、原儿茶素葡萄糖苷、锦葵素、anigorufone、羟基 anigorufone、β-咔啉生物碱和 VIDR-2T、VIDR-2GC、VIDR-2GD 等馏分。药理学研究表明,芭蕉芋无毒(LD=3235.9mg/kg),具有抗尿石症、抗糖尿病、抗生育、抗雌激素、抗病毒、心血管和抗炎活性。

结论

芭蕉芋可能是人类和动物安全有效药用和营养草药的绝佳来源。

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