Fernando Oñorbe San Francisco, Supreeth Nekkanti, David Guzman Domenech, Borja LimousinAranzabal, Ricardo LarrainzarGarijo
Department of Orthopaedics, Hospital Infanta Leonor, Madrid, Spain.
J Orthop Case Rep. 2018 Jul-Aug;8(4):11-14. doi: 10.13107/jocr.2250-0685.1136.
Ochronosis is an inherited metabolic disease that causes a brownish-black pigmentation of the connective tissue. There is currently no specific treatment for ochronosis. The goal of treatment is to control the progress of disease with a multidisciplinary approach and symptomatic relief. Arthroplasty in ochronotic arthropathy patients has shown good to excellent results comparable to arthroplasty performed in patients with degenerative osteoarthritis.
We report an unusual case of a 69-year-old female who suffered advanced degenerative arthropathy secondary to ochronosis. A staged bilateral total hip arthroplasty was performed on her successfully using a Corail metal on poly total hip prosthesis 9months apart.
Ochronoticarthropathy produces degenerative arthritis of large joints in middle-aged patients. In many cases, the patient does not know the disease until the diagnosis of intraoperative suspicion. There is no definitive treatment. After conservative management, joint replacement surgery offers the best symptomatic treatment.
褐黄病是一种遗传性代谢疾病，可导致结缔组织出现棕黑色色素沉着。目前尚无针对褐黄病的特效治疗方法。治疗的目标是采用多学科方法控制疾病进展并缓解症状。褐黄病性关节病患者的关节置换术已显示出与退行性骨关节炎患者进行的关节置换术相当的良好至优异效果。
我们报告了一例不寻常的病例，一名69岁女性患有继发于褐黄病的晚期退行性关节病。使用Corail金属对聚乙烯全髋关节假体，在9个月的间隔时间内为她成功实施了分期双侧全髋关节置换术。
褐黄病性关节病在中年患者中会导致大关节的退行性关节炎。在许多情况下，患者直到术中怀疑诊断时才知道自己患有这种疾病。目前尚无确切的治疗方法。经过保守治疗后，关节置换手术是最佳的对症治疗方法。
