中毒性休克综合征
Toxic shock syndrome.
作者信息
Todd J K
机构信息
Children's Hospital Kempe Research Center, Denver, Colorado 80218.
出版信息
Clin Microbiol Rev. 1988 Oct;1(4):432-46. doi: 10.1128/CMR.1.4.432.
Abstract
In the past 10 years, we have learned much about TSS and S. aureus and its toxins. A number of important biologic principles have been reemphasized in this first decade of TSS research: S. aureus is a very complex organism, one not likely to yield quick answers; in vitro observations must always be confirmed in the patient; animal models may not always be reliable replicates of human disease; and epidemiologic associations cannot be equated with causation. Toxic shock is an intricate phenomenon with many interesting scientific facets. Unraveling its mysteries will undoubtedly teach us more about the complex interaction of patients and microorganisms.
摘要
在过去十年中，我们对中毒性休克综合征（TSS）、金黄色葡萄球菌及其毒素有了很多了解。在TSS研究的第一个十年里，一些重要的生物学原理被再次强调：金黄色葡萄球菌是一种非常复杂的生物体，不太可能迅速得出答案；体外观察结果必须在患者身上得到证实；动物模型不一定总是人类疾病的可靠复制品；而且流行病学关联不能等同于因果关系。中毒性休克是一种复杂的现象，有许多有趣的科学方面。解开它的谜团无疑将使我们更多地了解患者与微生物之间的复杂相互作用。
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Toxic-shock syndrome in menstruating women: association with tampon use and Staphylococcus aureus and clinical features in 52 cases.经期女性中毒性休克综合征：与使用卫生棉条及金黄色葡萄球菌的关联及52例临床特征
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