Hypoxia-inducible factor-1 α and RIP3 triggers NLRP3 inflammasome in ischemic stroke.
作者信息
Jiang Qian, Stone Christopher R, Geng Xiaokun, Ding Yuchuan
机构信息
China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, USA.
出版信息
Brain Circ. 2018 Oct-Dec;4(4):191-192. doi: 10.4103/bc.bc_35_18. Epub 2018 Dec 31.
Abstract
摘要
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Inflammasome: Its role in traumatic brain and spinal cord injury.炎症小体：在创伤性脑和脊髓损伤中的作用。
J Cell Physiol. 2018 Jul;233(7):5160-5169. doi: 10.1002/jcp.26287. Epub 2018 Jan 19.
3
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MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D.混合谱系激酶结构域样蛋白（MLKL）的激活触发NLRP3介导的白细胞介素-1β（IL-1β）的加工和释放，且不依赖于gasdermin-D。
J Immunol. 2017 Mar 1;198(5):2156-2164. doi: 10.4049/jimmunol.1601757. Epub 2017 Jan 27.
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