Gamper Eva-Maria, Martini Caroline, Petersen Morten Aagaard, Virgolini Irene, Holzner Bernhard, Giesinger Johannes M
Innsbruck Institute of Patient-centered Outcome Research (IIPCOR), Dr. Stumpf Strasse 56, 6020, Innsbruck, Austria.
Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatry II, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
J Patient Rep Outcomes. 2019 Jan 29;3(1):7. doi: 10.1186/s41687-019-0096-3.
Computer-adaptive tests (CAT) use individualised sets of questions to assess patient-reported health states, whereas static (conventional) questionnaires present the same questions to all patients. CAT has been shown to increase measurement precision and reduce assessment length. In our study, we investigated if patients perceive CAT questions as more appropriate than static questionnaires, a claim that is frequently associated with CAT measures.
We compared the static European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) against its corresponding CAT measures focusing on two domains: Physical Functioning (PF) and Emotional Functioning (EF). Cancer patients completed the questionnaires and participated in a cognitive interview to assess how appropriate they perceive the QLQ-C30 and the CAT questions for their current health state.
Forty-four cancer patients (mean age = 54.6; 56.8% female) were assessed. For the PF domain, patients considered the CAT items more appropriate (p = 0.002) than the QLQ-C30 items (56.8% vs. 15.9%; 27.2% indifferent). For the EF domain, patients were in favour of the QLQ-C30 items (p < 0.001), with 54.5% considering the QLQ-C30, and 4.5% considering the CAT items to be more appropriate; 40.9% were indifferent. Most patients (N = 36) commented on the preference for the CAT (PF), mentioning better matching of the questions and the health state (38.6%) and better item wording (15.9%).
For the PF domain the CAT measure better matched the score distribution in the patient sample than the QLQ-C30 PF scale and was consequently considered more appropriate by patients. For the EF domain, the CAT measure did not show better fit than the QLQ-C30 and hence no such preference in terms of appropriateness was observed.
计算机自适应测试(CAT)使用个性化的问题集来评估患者报告的健康状况,而静态(传统)问卷则向所有患者呈现相同的问题。研究表明,CAT可提高测量精度并缩短评估时间。在我们的研究中,我们调查了患者是否认为CAT问题比静态问卷更合适,这一说法常与CAT测量相关。
我们将静态的欧洲癌症研究与治疗组织生活质量问卷核心30项(EORTC QLQ-C30)与其相应的CAT测量进行了比较,重点关注两个领域:身体功能(PF)和情绪功能(EF)。癌症患者完成问卷并参与认知访谈,以评估他们认为QLQ-C30和CAT问题对于其当前健康状况的合适程度。
对44名癌症患者(平均年龄=54.6岁;56.8%为女性)进行了评估。对于PF领域,患者认为CAT项目比QLQ-C30项目更合适(p=0.002)(56.8%对15.9%;27.2%无差异)。对于EF领域,患者更倾向于QLQ-C30项目(p<0.001),54.5%的患者认为QLQ-C30更合适,4.5%的患者认为CAT项目更合适;40.9%的患者无差异。大多数患者(N=36)表达了对CAT(PF)的偏好,提到问题与健康状况的匹配度更高(38.6%)以及项目措辞更好(15.9%)。
对于PF领域,CAT测量比QLQ-C30 PF量表更能匹配患者样本中的得分分布,因此患者认为其更合适。对于EF领域,CAT测量并未显示出比QLQ-C30更好的拟合度,因此在合适性方面未观察到此类偏好。