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慢性炎症性回肠造口部位皮肤叠加皮肤疣状癌:一例报告

Cutaneous Verrucous Carcinoma Superimposed on Chronically Inflamed Ileostomy Site Skin: A Case Report.

作者信息

Yaghobi Joybari Ali, Azadeh Payam, Nemati Honar Behzad

机构信息

Dept. of Radiation Oncology, School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.

Dept. of Surgery, School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.

出版信息

Iran J Pathol. 2018 Spring;13(2):285-288. Epub 2018 Jul 17.

PMID:30697301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6339498/
Abstract

Verrucous carcinoma (VC) is a rare variant of well differentiated squamous cell carcinoma (SCC) which is usually found in oral cavity mucosa. Cutaneous verrucous carcinoma is a rare entity and in this paper we report a 43 years old man with VCsuperimposed on chronically inflamed skin of ileostomy site. Previously, he was operated to treat rectal adenocarcinoma and has had ileostomy for six months. The skin lesion was resected totally during surgical operation for ileostomy closure. Histopathologic examination confirmed the diagnosis of cutaneous verrucous carcinoma. Post-operative follow up shows no evidence of recurrence after six months. We suggest patient's training for follow up visits in order to early detection of osteomy site complications including neoplastic changes.

摘要

疣状癌(VC)是一种罕见的高分化鳞状细胞癌(SCC)变体,通常见于口腔黏膜。皮肤疣状癌是一种罕见的疾病,在本文中,我们报告了一名43岁男性,其在慢性炎症的回肠造口部位皮肤叠加了疣状癌。此前,他接受了直肠腺癌手术,回肠造口已进行了6个月。在回肠造口关闭的手术中,皮肤病变被完全切除。组织病理学检查确诊为皮肤疣状癌。术后随访6个月显示无复发迹象。我们建议对患者进行随访培训,以便早期发现包括肿瘤性改变在内的造口部位并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d296/6339498/6ab0f32e4722/ijp-13-285-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d296/6339498/c7ea8ad61401/ijp-13-285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d296/6339498/6ab0f32e4722/ijp-13-285-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d296/6339498/c7ea8ad61401/ijp-13-285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d296/6339498/6ab0f32e4722/ijp-13-285-g002.jpg

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Cutaneous Verrucous Carcinoma Superimposed on Chronically Inflamed Ileostomy Site Skin: A Case Report.慢性炎症性回肠造口部位皮肤叠加皮肤疣状癌:一例报告
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本文引用的文献

1
A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma ("the Bad Kind" of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report.疣状鳞状细胞癌(“恶性”角化病)的疑难诊断及临床与病理关联的必要性:文献综述及病例报告
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Verrucous carcinoma of the oral cavity.口腔疣状癌
Surgery. 1948 Apr;23(4):670-8.
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Verrucous carcinoma of the oral cavity: A clinical and pathological study of 101 cases.口腔疣状癌:101例临床病理研究
Oral Oncol. 2009 Jan;45(1):47-51. doi: 10.1016/j.oraloncology.2008.03.014. Epub 2008 Jul 11.
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Human papillomavirus infection in oral verrucous carcinoma: genotyping analysis and inverse correlation with p53 expression.口腔疣状癌中的人乳头瘤病毒感染:基因分型分析及与p53表达的负相关
Pathobiology. 2008;75(4):257-64. doi: 10.1159/000132387. Epub 2008 Jun 26.
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Verrucous carcinoma, then and now.疣状癌,过去与现在。
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Presence of human papillomavirus type 16 related sequences in verrucous carcinoma of the larynx.喉疣状癌中16型人乳头瘤病毒相关序列的存在
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