Ito Yusuke, Nishijima Hironobu, Kishimoto Seiji
Department of Otorhinolaryngology and Head and Neck Surgery, Kameda Medical Center, Chiba, JPN.
Department of Head and Neck Surgery, National Cancer Center Hospital East, Chiba, JPN.
Cureus. 2021 May 22;13(5):e15162. doi: 10.7759/cureus.15162.
Verrucous carcinoma (VC) is a rare subtype of squamous cell carcinoma. VC commonly occurs in the mucosa, but rarely occurs in the skin. The treatment for VC is surgical removal of the tumor. Because lymph node metastasis of VC is rare, the indications for prophylactic neck dissection for cutaneous VC of the neck are controversial. Here, we present the case of a 68-year-old man with a huge cutaneous VC of the neck and the long-term clinical course. The tumor occupied the entire right cervical skin, with suspected lymph node metastasis in the affected neck. Tumor resection and neck lymph node dissection were performed. Pathological examination revealed cutaneous VC with invasion to the adjacent tissues and no lymph node metastasis. Cutaneous VC of the neck is likely to grow locally without regional lymph node metastasis regardless of the long-term course and the size of the tumor.
疣状癌（VC）是鳞状细胞癌的一种罕见亚型。VC常见于黏膜，但很少发生于皮肤。VC的治疗方法是手术切除肿瘤。由于VC很少发生淋巴结转移，颈部皮肤VC预防性颈清扫术的指征存在争议。在此，我们报告一例68岁男性颈部巨大皮肤VC及其长期临床病程。肿瘤占据了整个右侧颈部皮肤，患侧颈部怀疑有淋巴结转移。进行了肿瘤切除和颈部淋巴结清扫术。病理检查显示为皮肤VC，侵犯相邻组织，无淋巴结转移。无论病程长短和肿瘤大小，颈部皮肤VC可能在局部生长而无区域淋巴结转移。
