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工作年龄人群中的晕厥:复发风险及相关危险因素

Syncope in a Working-Age Population: Recurrence Risk and Related Risk Factors.

作者信息

Barbic Franca, Dipaola Franca, Casazza Giovanni, Borella Marta, Minonzio Maura, Solbiati Monica, Raj Satish R, Sheldon Robert, Quinn James, Costantino Giorgio, Furlan Raffaello

机构信息

Internal Medicine, Humanitas Clinical and Research Center, Biomedical Sciences Department, Humanitas University, 20089 Rozzano, Italy.

Dipartimento di Scienze Biomediche e Cliniche "L. Sacco"-Università degli Studi di Milano, 20157 Milan, Italy.

出版信息

J Clin Med. 2019 Jan 29;8(2):150. doi: 10.3390/jcm8020150.

DOI:10.3390/jcm8020150
PMID:30699893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6406660/
Abstract

Syncope in a worker undertaking risky tasks may result in fatalities for the individual or for third parties. We aimed at assessing the rate of syncope recurrence and the risk factors underlying the likelihood of syncope relapse in a working-age population. A prospective cohort of all patients aged 18⁻65 years consecutively admitted to the Emergency Department for syncope was enrolled. Risk of syncope relapse was assessed at a six-month, 1-year, and 5-year follow-up. Predictors of syncope recurrence have been evaluated at six months and 1 year from the syncope index by a multivariable logistic regression analysis. 348 patients were enrolled. Risk of syncope relapse was 9.2% at 6 months, 11.8% at 1 year, and 23.4% at 5 years. At 6-month follow-up, predictor of syncope recurrence was ≥3 prior lifetime syncope episodes. At 1-year, ≥3 prior lifetime syncope episodes, diabetes mellitus, and anaemia were risk factors for syncope relapse. There was an exceeding risk of recurrence in the first 6 months and a reduced risk of 3.5% per year after the first year. Anaemia, diabetes mellitus, and prior lifetime syncope burden are of importance when giving advice about the resumption of "high risk" jobs following a syncope episode.

摘要

从事危险任务的工人发生晕厥可能会导致个人或第三方死亡。我们旨在评估工作年龄人群中晕厥复发率以及晕厥复发可能性背后的风险因素。纳入了所有年龄在18至65岁之间因晕厥连续入住急诊科的患者组成的前瞻性队列。在6个月、1年和5年的随访中评估晕厥复发风险。通过多变量逻辑回归分析在距晕厥指数6个月和1年时评估晕厥复发的预测因素。共纳入348例患者。晕厥复发风险在6个月时为9.2%,1年时为11.8%,5年时为23.4%。在6个月的随访中,晕厥复发的预测因素是既往有≥3次晕厥发作。在1年时,既往有≥3次晕厥发作、糖尿病和贫血是晕厥复发的风险因素。在最初6个月内复发风险较高,而在第1年后每年复发风险降低3.5%。在就晕厥发作后恢复“高风险”工作提供建议时,贫血、糖尿病和既往晕厥负担很重要。

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本文引用的文献

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2018 ESC Guidelines for the diagnosis and management of syncope.2018年欧洲心脏病学会晕厥诊断和管理指南。
Eur Heart J. 2018 Jun 1;39(21):1883-1948. doi: 10.1093/eurheartj/ehy037.
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Syncope Prognosis Based on Emergency Department Diagnosis: A Prospective Cohort Study.基于急诊科诊断的晕厥预后:一项前瞻性队列研究。
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晕厥的心理因素及其与复发的可能关联——植入式循环记录仪的作用
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Association of Occupational Distress and Low Sleep Quality with Syncope, Presyncope, and Falls in Workers.职业压力和睡眠质量差与工人晕厥、先兆晕厥和跌倒的关联。
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Syncope, Fear of Falling and Quality of Life Among Older Adults: Findings From the Irish Longitudinal Study on Aging (TILDA).老年人的晕厥、跌倒恐惧与生活质量:爱尔兰纵向老龄化研究(TILDA)的结果
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Syncope and Its Impact on Occupational Accidents and Employment: A Danish Nationwide Retrospective Cohort Study.晕厥及其对职业事故和就业的影响:一项丹麦全国性回顾性队列研究。
Circ Cardiovasc Qual Outcomes. 2017 Apr;10(4). doi: 10.1161/CIRCOUTCOMES.116.003202.
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Nationwide Trends in Syncope Hospitalizations and Outcomes From 2004 to 2014.2004年至2014年全国晕厥住院情况及治疗结果的趋势
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Fludrocortisone for the Prevention of Vasovagal Syncope: A Randomized, Placebo-Controlled Trial.氟氢可的松预防血管迷走性晕厥的随机、安慰剂对照试验。
J Am Coll Cardiol. 2016 Jul 5;68(1):1-9. doi: 10.1016/j.jacc.2016.04.030.
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Assessment of a structured management pathway for patients referred to the Emergency Department for syncope: results in a tertiary hospital.对因晕厥转诊至急诊科的患者采用结构化管理路径的评估:一家三级医院的结果
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