McCarthy Kevin, Ward Mark, Romero Ortuño Román, Kenny Rose Anne
The Irish Longitudinal Study on Ageing (TILDA), Department of Medical Gerontology, Trinity College Dublin, Dublin, Ireland.
Mercer's Institute for Successful Ageing, St. James's Hospital, Dublin, Ireland.
Front Cardiovasc Med. 2020 Feb 7;7:7. doi: 10.3389/fcvm.2020.00007. eCollection 2020.
Syncope is a prevalent condition that has a marked impact on quality of life. We examined the association between syncope and quality of life (QoL) and whether this association was explained by fear of falling (FoF). We examined data from Wave 3 of The Irish Longitudinal Study on Aging (TILDA), of adults aged ≥50 years ( = 4,946) who were asked to report syncope and who completed the CASP-12 QoL instrument. Analyses were stratified by age and gender. Over 20% of participants reported having a previous syncopal episode, while 8% reported a faint, blackout or unexplained fall in the last year. QoL scores decreased as the burden of syncope increased: linear regression models adjusted for covariates showed that those having had two or more syncopal episodes in the last year reported a significantly lower CASP-12 score compared to those with none ( = 0.011). FoF partially mediated the association between syncope and QoL, particularly among younger participants. Syncope is a common condition among older adults that has a deleterious effect on QoL, with ≥2 recent syncopal episodes having a particularly adverse impact on QoL. FoF is a potential pathway which may both explain this association and allow therapeutic interventions by health practitioners.
晕厥是一种普遍存在的病症，对生活质量有显著影响。我们研究了晕厥与生活质量（QoL）之间的关联，以及这种关联是否由害怕跌倒（FoF）所解释。我们分析了爱尔兰纵向老龄化研究（TILDA）第3波的数据，研究对象为年龄≥50岁的成年人（n = 4,946），他们被要求报告晕厥情况并完成了CASP - 12生活质量量表。分析按年龄和性别分层。超过20%的参与者报告曾有过晕厥发作，而8%的参与者报告在过去一年中有过头晕、昏厥或不明原因的跌倒。生活质量得分随着晕厥负担的增加而降低：经协变量调整的线性回归模型显示，与没有晕厥发作的人相比，过去一年中有两次或更多次晕厥发作的人报告的CASP - 12得分显著更低（P = 0.011）。害怕跌倒部分介导了晕厥与生活质量之间的关联，尤其是在年轻参与者中。晕厥在老年人中是一种常见病症，对生活质量有有害影响，近期有≥2次晕厥发作对生活质量有特别不利的影响。害怕跌倒是一条潜在途径，它既可以解释这种关联，也能让医疗从业者进行治疗干预。
