Kaminishi H, Hagihara Y, Tanaka M, Cho T
Department of Oral Microbiology, Fukuoka Dental College, Japan.
J Med Vet Mycol. 1988;26(5):315-8.
Candida albicans, when cultivated in a medium containing insoluble bovine achilles tendon as a nitrogen source, was able to produce a collagen degrading proteinase. The degradation of achilles tendon collagen by the proteinase was verified by morphological change and the release of hydroxyproline. The proteinase activity was inhibited by pepstatin.