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接受高效抗逆转录病毒治疗药物的泰国HIV阳性患者口腔中的非口腔需氧革兰氏阴性杆菌

Non-oral, aerobic, Gram-negative bacilli in the oral cavity of Thai HIV-positive patients on Highly-active anti-retrovirus therapy medication.

作者信息

Arirachakaran Pratanporn, Luangworakhun Sureeat, Charalampakis Georgios, Dahlén Gunnar

机构信息

Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University and Dental Center, Bangkok Hospital, Bangkok, Thailand.

Oral Research Center, Faculty of Dentistry, Chulalongkorn University, Chulalongkorn, Thailand.

出版信息

J Investig Clin Dent. 2019 May;10(2):e12387. doi: 10.1111/jicd.12387. Epub 2019 Jan 30.

DOI:10.1111/jicd.12387
PMID:30701696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6590175/
Abstract

In the present study, we identified and evaluated the antibiotic susceptibility of 96 independent, aerobic, Gram-negative bacillus isolates from 255 Thai HIV-positive adults who were on Highly-active anti-retrovirus therapy (HAART) medication. Another 46 isolates from HIV non-HAART individuals, vertically transmitted HIV-positive individuals, and non-HIV controls were included for comparison. A total of 103 strains were tested for antibiotic susceptibility using disc diffusion for screening and E-test for minimal inhibitory concentration determination, with special attention on extended-spectrum beta-lactamase (ESBL) isolates. Pseudomonas aeruginosa, Pseudomonas luteola, Burkholderia cepacia, Aeromonas hydrophila, Klebsiella, and Enterobacter species were the most common bacteria. All strains were resistant against penicillin, amoxicillin, clindamycin, and metronidazole. No ESBL isolates were found.

摘要

在本研究中，我们对来自255名接受高效抗逆转录病毒疗法（HAART）治疗的泰国HIV阳性成年人的96株独立、需氧、革兰氏阴性杆菌分离株进行了鉴定和抗生素敏感性评估。另外还纳入了46株来自未接受HAART治疗的HIV感染者、垂直传播的HIV阳性个体以及非HIV对照个体的分离株用于比较。使用纸片扩散法进行筛选，E-test法测定最低抑菌浓度，共对103株菌株进行了抗生素敏感性测试，特别关注产超广谱β-内酰胺酶（ESBL）的分离株。铜绿假单胞菌、浅黄假单胞菌、洋葱伯克霍尔德菌、嗜水气单胞菌、克雷伯菌属和肠杆菌属是最常见的细菌。所有菌株对青霉素、阿莫西林、克林霉素和甲硝唑均耐药。未发现产ESBL的分离株。

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本文引用的文献

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Br Dent J. 2016 Nov 18;221(10):657-666. doi: 10.1038/sj.bdj.2016.865.
2
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Microb Pathog. 2016 May;94:117-22. doi: 10.1016/j.micpath.2016.01.020. Epub 2016 Feb 2.
3
Dental and microbiological risk factors for hospital-acquired pneumonia in non-ventilated older patients.非通气老年患者医院获得性肺炎的口腔和微生物危险因素
PLoS One. 2015 Apr 29;10(4):e0123622. doi: 10.1371/journal.pone.0123622. eCollection 2015.
4
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Pathog Glob Health. 2014 Jul;108(5):235-45. doi: 10.1179/2047773214Y.0000000148. Epub 2014 Aug 21.
6
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8
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10
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FEMS Immunol Med Microbiol. 2010 Oct;60(1):1-17. doi: 10.1111/j.1574-695X.2010.00709.x.