University of Rochester Medical Center, Rochester, NY, USA.
Am Fam Physician. 2019 Feb 1;99(3):159-165.
Acute gastroenteritis is defined as a diarrheal disease of rapid onset, with or without nausea, vomiting, fever, or abdominal pain. In the United States, acute gastroenteritis accounts for 1.5 million office visits, 200,000 hospitalizations, and 300 deaths in children each year. Evaluation of a child with acute gastroenteritis should include a recent history of fluid intake and output. Significant dehydration is unlikely if parents report no decrease in oral intake or urine output and no vomiting. The physical examination is the best way to evaluate hydration status. The four-item Clinical Dehydration Scale can be used to determine severity of dehydration based on physical examination findings. In children with mild illness, stool microbiological tests are not routinely needed when viral gastroenteritis is the likely diagnosis. Mild gastroenteritis in children can be managed at home. Oral rehydration therapy, such as providing half-strength apple juice followed by the child's preferred liquids, is the mainstay of treatment for mild dehydration and is as effective as intravenous rehydration for preventing hospitalization and return to the emergency department. Oral rehydration solutions are recommended for moderate dehydration. Ondansetron may be prescribed if needed to prevent vomiting and improve tolerance of oral rehydration solutions. Hospitalization and intravenous fluids are recommended for children who do not respond to oral rehydration therapy plus an antiemetic and patients with severe dehydration (i.e., signs of shock or more than 10% dehydration). Handwashing, breastfeeding, and rotavirus vaccination reduce the incidence of acute gastroenteritis in young children.
急性肠胃炎定义为一种发病迅速的腹泻疾病,伴有或不伴有恶心、呕吐、发热或腹痛。在美国,急性肠胃炎每年导致 150 万次门诊就诊、20 万次住院治疗和 300 例儿童死亡。评估患有急性肠胃炎的儿童时,应包括近期液体摄入和排出量的病史。如果父母报告没有减少口腔摄入或尿液排出量且没有呕吐,则不太可能出现明显脱水。体格检查是评估脱水状态的最佳方法。四项临床脱水量表可根据体格检查结果来确定脱水的严重程度。对于轻度疾病的儿童,如果疑似病毒性肠胃炎,通常不需要进行粪便微生物检测。儿童轻度肠胃炎可在家中进行管理。口服补液疗法,如提供半强度苹果汁,然后是患儿喜欢的液体,是治疗轻度脱水的主要方法,与静脉补液一样有效,可预防住院和返回急诊部。对于中度脱水,推荐口服补液溶液。如果需要预防呕吐和提高口服补液溶液的耐受性,可以开昂丹司琼。对于不接受口服补液治疗加止吐药的患儿以及严重脱水(即休克迹象或脱水超过 10%)的患者,建议住院并给予静脉输液。勤洗手、母乳喂养和轮状病毒疫苗接种可降低幼儿急性肠胃炎的发生率。