Tracking myeloid malignancies by targeted analysis of successive DNA methylation at neighboring CG dinucleotides.
作者信息
Eipel Monika, Božić Tanja, Mies Anna, Beier Fabian, Jost Edgar, Brümmendorf Tim H, Platzbecker Uwe, Wagner Wolfgang
机构信息
Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, RWTH Aachen University, Aachen.
Universitätsklinikum Carl Gustav Carus der TU Dresden, Medizinische Klinik und Poliklinik I, Dresden.
出版信息
Haematologica. 2019 Aug;104(8):e349-e351. doi: 10.3324/haematol.2018.209734. Epub 2019 Jan 31.
Abstract
摘要
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Senescence-associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells.衰老相关的DNA甲基化是在间充质干细胞亚群中随机获得的。
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