Rabina Gilad, Azem Nur, Barequet Dana, Barak Adiel, Loewenstein Anat, Schwartz Shulamit
Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Retina. 2020 May;40(5):998-1004. doi: 10.1097/IAE.0000000000002464.
To evaluate the influence of silicone oil (SO) tamponade on retinal layers thickness and visual acuity in patients who underwent pars plana vitrectomy for rhegmatogenous retinal detachment.
This is a retrospective case series of consecutive patients who underwent pars plana vitrectomy for rhegmatogenous retinal detachment with SO tamponade. Visual acuity and central macular thickness were measured with SO and at least a month after SO removal (SOR). Patients with insufficient or poor-quality images or macular pathologies such as macular edema or epiretinal membranes were excluded.
Forty-one patients with an average age of 56.1 ± 15.2 years were included, and 54% presented with fovea ON. Average tamponade duration was 151 ± 54 days. Central macular thickness of the operated eye increased from 249 ± 50 µm before to 279 ± 48 µm after SOR (P < 0.001), compared with 281 ± 21 µm of the fellow eye (P < 0.001). A mean change of 26 µm was found in the internal layers (P < 0.001). Visual acuity improved from 0.85 ± 0.97 logarithm of the minimal angle of resolution (logMAR; Snellen 20/140) with SO tamponade to 0.34 ± 0.28 logMAR (Snellen 20/43) after SOR (P < 0.001). For patients with fovea ON and without significant cataract, visual acuity was 0.19 ± 0.16 logMAR (Snellen 20/30) at presentation, 0.59 ± 0.41 logMAR (Snellen 20/80) with SO (P = 0.005), and 0.18 ± 0.15 logMAR (Snellen 20/30) after SOR (P = 0.003).
Silicone oil tamponade causes a transient decrease in central macular thickness, mainly in the inner layers. After SOR, central macular thickness resembles to the fellow eyes. The mechanism for this effect is unclear, but apparently has no influence on final visual acuity.
评估硅油（SO）填塞对孔源性视网膜脱离患者行玻璃体切割术后视网膜各层厚度及视力的影响。
这是一项回顾性病例系列研究，纳入连续接受玻璃体切割联合SO填塞治疗孔源性视网膜脱离的患者。分别在使用SO时及取出SO（SOR）后至少1个月测量视力和黄斑中心厚度。排除图像质量不佳或存在黄斑病变（如黄斑水肿或视网膜前膜）的患者。
纳入41例患者，平均年龄56.1±15.2岁，其中54%患者黄斑中心凹为正视状态。平均填塞时间为151±54天。手术眼的黄斑中心厚度从SOR前的249±50μm增加至SOR后的279±48μm（P<0.001），而对侧眼为281±21μm（P<0.001）。内层平均变化为26μm（P<0.001）。视力从使用SO填塞时的0.85±0.97最小分辨角对数（logMAR；Snellen 20/140）提高至SOR后的0.34±0.28 logMAR（Snellen 20/43）（P<0.001）。对于黄斑中心凹为正视且无明显白内障的患者，初诊时视力为0.19±0.16 logMAR（Snellen 20/30），使用SO时为
