Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya St., 6, Moscow 105064, Russia; Yaroslavl State University, Sovetskaya St., 14, Yaroslavl 150000, Russia; IM Sechenov First Moscow State Medical University, Bolshaya Pirogovskaya St., 8, Moscow 119146, Russia; Federal Research Centre of Biological Systems and Agro-technologies of the Russian Academy of Sciences, 9 Yanvarya St., 29, Orenburg 460000, Russia.
Orenburg State University, Pobedy Ave., 13, Orenburg 460352, Russia.
Environ Res. 2019 Apr;171:293-301. doi: 10.1016/j.envres.2019.01.038. Epub 2019 Jan 25.
The objective of the present study was investigation of the selenium (Se) levels in environmental samples, main consumed food products, as well as human hair in the areas of the Orenburg region. Se levels in the environmental objects (water, soil, wheat), frequently consumed food products (wheat bread, ryebread, beef, pork, chicken, milk, cottage cheese), as well as human hair samples in the western (n = 210), central (n = 195), and eastern (n = 120) areas were assessed using inductively-coupled plasma mass-spectrometry and atomic absorption spectrometry (soil). The obtained data demonstrate that water (87% and 89%), soil (41% and 48%), and wheat (11% and 11%) Se levels Central and Eastern areas were significantly higher than those in the Western area. The level of Se in foods was found to be the highest in the Eastern (wheat bread and beef), Central and Eastern (ryebread and pork), or Central (milk and cottage cheese) areas of the Orenburg region. Hair Se content (0.298 (0.233-0.591) μg/g) as well as dietary Se intake (84.3 (73.7-95.8) μg/day) did not differ significantly between the studied areas. At the same time, regression analysis demonstrated that Se intake with wheat bread (β = 0.634; p = 0.042) was the strongest predictor of hair Se. The revealed associations between environmental and food Se content and Se status of the population underline the necessity of continuous monitoring of Se intake and exposure in order to prevent potential health effects associated with both deficiency and overload.
本研究的目的是调查奥伦堡地区环境样本、主要消费食品以及人发中的硒（Se）水平。采用电感耦合等离子体质谱法和原子吸收光谱法（土壤）评估了环境物体（水、土壤、小麦）、常食用的食品（小麦面包、黑麦面包、牛肉、猪肉、鸡肉、牛奶、奶酪）以及西部（n=210）、中部（n=195）和东部（n=120）地区人发样本中的 Se 水平。结果表明，中部和东部地区水（87%和 89%）、土壤（41%和 48%）和小麦（11%和 11%）的 Se 水平显著高于西部地区。食物中的 Se 水平在奥伦堡地区东部（小麦面包和牛肉）、中部和东部（黑麦面包和猪肉）或中部（牛奶和奶酪）最高。头发中的 Se 含量（0.298（0.233-0.591）μg/g）以及膳食 Se 摄入量（84.3（73.7-95.8）μg/天）在研究区域之间没有显著差异。同时，回归分析表明，小麦面包的 Se 摄入量（β=0.634；p=0.042）是头发 Se 的最强预测因子。环境和食物中的 Se 含量与人群中的 Se 状况之间的关联表明，需要持续监测 Se 的摄入和暴露，以防止与缺乏和过载相关的潜在健康影响。
