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成纤维细胞:危险的旅伴。

Fibroblasts: Dangerous travel companions.

机构信息

Department of Pathology, The University of Chicago, Chicago, IL

出版信息

J Exp Med. 2019 Mar 4;216(3):479-481. doi: 10.1084/jem.20181850. Epub 2019 Feb 1.

Abstract

In this issue of , Gao et al. (https://doi.org/10.1084/jem.20180765) demystify the exceptional metastatic success of ovarian cancer, the most lethal female malignancy: fibroblasts form heterotypic aggregates with disseminating cancer cells, thereby providing them with reciprocal signaling and matrix for adherence.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/208c/6400545/5ed156cd2f3b/JEM_20181850_Fig1.jpg

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