Department of Nephrology, Dialysis and Transplantation and International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy,
Department of Nephrology, Dialysis and Transplantation and International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy.
Blood Purif. 2019;48(1):60-66. doi: 10.1159/000496090. Epub 2019 Feb 1.
ACUsmart (Medica S.P.A., Italy) is a new-generation, continuous renal replacement therapy (CRRT) machine for critically ill patients with acute kidney injury. We designed a multicenter international pilot study to provide a description of outlines of the ACUsmart system, evaluation aspects of functionality, usability, and feasibility, discriminating reasons of possible treatment's withdrawals or discontinuations and highlighting strong and weak points of the machine.
Data of 23 CRRT (and 11 plasma exchange) treatments were collected from 4 intensive care units. Parameters such as treatment duration, downtime, delivered dose, and number and type of alarms were recorded. The general perception of the machine was quantified through the administration of a survey to each component of the evaluating staff.
A total treatment time of 447 h was carried with ACUsmart. Eleven continuous veno-venous hemofiltration, 4 continuous veno-venous hemodialysis , and 8 continuous veno-venous hemodiafiltration were performed. The average percentage of net treatment duration with respect to total treatment duration was 92.37%. The mean prescribed dose and delivered dose were 26.33 and 24.10 mL/kg/h, respectively. In general, the machine was rated by users involved as practical and easy to use, although few components need to be slightly improved.
ACUsmart is a new multifunctional machine that meets most of the features required in a fourth-generation CRRT equipment.
ACUsmart（意大利 Medica S.P.A.）是一款新一代的连续肾脏替代治疗（CRRT）设备，适用于患有急性肾损伤的重症患者。我们设计了一项多中心国际试点研究，旨在提供 ACUsmart 系统的概述描述，评估其功能、可用性和可行性，区分可能导致治疗中断或停止的原因，并突出机器的优点和缺点。
从 4 个重症监护病房收集了 23 次 CRRT（和 11 次血浆置换）治疗的数据。记录了治疗持续时间、停机时间、输送剂量以及报警次数和类型等参数。通过向评估人员的每个组成部分发放调查，对机器的总体感觉进行量化。
使用 ACUsmart 进行了总计 447 小时的治疗。进行了 11 次连续静脉-静脉血液滤过、4 次连续静脉-静脉血液透析和 8 次连续静脉-静脉血液透析滤过。相对于总治疗时间，实际治疗时间的平均百分比为 92.37%。规定的剂量和输送剂量分别为 26.33 和 24.10 mL/kg/h。总体而言，使用者认为该机器实用且易于使用，尽管少数组件需要略微改进。
ACUsmart 是一款新型多功能机器，满足了第四代 CRRT 设备的大多数要求。
