Smith Fawzi Mary C, Andrews Kathryn G, Fink Günther, Danaei Goodarz, McCoy Dana Charles, Sudfeld Christopher R, Peet Evan D, Cho Jeanne, Liu Yuanyuan, Finlay Jocelyn E, Ezzati Majid, Kaaya Sylvia F, Fawzi Wafaie W
Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
BMJ Glob Health. 2019 Jan 10;4(1):e001144. doi: 10.1136/bmjgh-2018-001144. eCollection 2019.
The first 1000 days of life is a period of great potential and vulnerability. In particular, physical growth of children can be affected by the lack of access to basic needs as well as psychosocial factors, such as maternal depression. The objectives of the present study are to: (1) quantify the burden of childhood stunting in low/middle-income countries attributable to psychosocial risk factors; and (2) estimate the related lifetime economic costs.
A comparative risk assessment analysis was performed with data from 137 low/middle-income countries throughout Asia, Latin America and the Caribbean, North Africa and the Middle East, and sub-Saharan Africa. The proportion of stunting prevalence, defined as <-2 SDs from the median height for age according to the WHO Child Growth Standards, and the number of cases attributable to low maternal education, intimate partner violence (IPV), maternal depression and orphanhood were calculated. The joint effect of psychosocial risk factors on stunting was estimated. The economic impact, as reflected in the total future income losses per birth cohort, was examined.
Approximately 7.2 million cases of stunting in low/middle-income countries were attributable to psychosocial factors. The leading risk factor was maternal depression with 3.2 million cases attributable. Maternal depression also demonstrated the greatest economic cost at $14.5 billion, followed by low maternal education ($10.0 billion) and IPV ($8.5 billion). The joint cost of these risk factors was $29.3 billion per birth cohort.
The cost of neglecting these psychosocial risk factors is significant. Improving access to formal secondary school education for girls may offset the risk of maternal depression, IPV and orphanhood. Focusing on maternal depression may play a key role in reducing the burden of stunting. Overall, addressing psychosocial factors among perinatal women can have a significant impact on child growth and well-being in the developing world.
生命的最初1000天是一个充满巨大潜力且脆弱的时期。特别是,儿童的身体发育可能会受到基本需求无法满足以及心理社会因素的影响,比如母亲抑郁。本研究的目的是:(1)量化中低收入国家因心理社会风险因素导致的儿童发育迟缓负担;(2)估算相关的终身经济成本。
利用来自亚洲、拉丁美洲和加勒比地区、北非和中东以及撒哈拉以南非洲的137个中低收入国家的数据进行了比较风险评估分析。计算了发育迟缓患病率(根据世界卫生组织儿童生长标准,定义为低于年龄别身高中位数2个标准差)以及可归因于低母亲教育水平、亲密伴侣暴力(IPV)、母亲抑郁和孤儿身份的病例数。估算了心理社会风险因素对发育迟缓的联合影响。研究了经济影响,以每个出生队列未来总收入损失来反映。
中低收入国家约720万例发育迟缓病例可归因于心理社会因素。主要风险因素是母亲抑郁,有320万例病例可归因于此。母亲抑郁造成的经济成本也最高,达145亿美元,其次是低母亲教育水平(100亿美元)和亲密伴侣暴力(85亿美元)。这些风险因素的联合成本为每个出生队列293亿美元。
忽视这些心理社会风险因素的代价巨大。改善女童接受正规中等教育的机会可能会抵消母亲抑郁、亲密伴侣暴力和孤儿身份的风险。关注母亲抑郁可能在减轻发育迟缓负担方面发挥关键作用。总体而言,解决围产期妇女的心理社会因素对发展中世界儿童的生长和福祉会产生重大影响。